Brewers vs. Cubs prediction: Why Cubs are favored to win Game 3 of NLDS [10/8/2025]

The Chicago Cubs will take on the Milwaukee Brewers in Game 3 of the National League Division Series at Wrigley Field on Wednesday, beginning at 5:08PM ET.

The Cubs will have Jameson Taillon (0-0, 0.00 ERA in 2025 postseason) as their starting pitcher, up against Quinn Priester (0-0, 0.00 ERA) for the Brewers.

Based on updated simulation results, Dimers' advanced MLB model predicts the Cubs as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Brewers-Cubs game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Cubs' chance of winning at 51%, with the Brewers at 49%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Brewers vs. Cubs predictions page.

Brewers vs. Cubs prediction: Who will win Game 3?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's MLB game between the Brewers and Cubs 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Cubs a 51% chance of defeating the Brewers.

According to our model, the 6.5-run over/under has a 67% chance of going over.

Brewers vs. Cubs Game 3 odds [10/8/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Brewers	Cubs
Moneyline	-108	-108
Total	o6.5 (-114)	u6.5 (-104)

All odds are correct at the time of publication and are subject to change.

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Brewers vs. Cubs picks and best bets for Game 3

Our model's biggest edge in today's Brewers vs. Cubs matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Brewers vs. Cubs game-day updates and essential details

Wednesday's MLB matchup between the Cubs and Brewers at Wrigley Field is scheduled to commence at 5:08PM ET.

• Who: Milwaukee Brewers vs. Chicago Cubs
• Date: Wednesday, October 8, 2025
• Time: 5:08PM ET/2:08PM PT
• Venue: Wrigley Field

Dimers' full preview of Wednesday's Brewers vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Brewers vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cubs, with a 51% win probability, will likely beat the Brewers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Brewers vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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