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Ohio State vs. Michigan State prediction: Why Michigan State is favored to win men's college basketball matchup [2/22/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Ohio State vs Michigan State predictions for college basketball Sunday.
Michigan State will square off with Ohio State in men's college basketball action at Jack Breslin Students Events Center on Sunday, commencing at 1:00 PM ET.
Based on the latest simulation results, Dimers' proven college basketball model predicts Michigan State as the most likely winner of the Ohio State vs. Michigan State game.
This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
Ohio State vs. Michigan State prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Sunday's NCAA basketball game between Ohio State and Michigan State 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives Michigan State an 86% chance of defeating Ohio State. Our predicted final score has Michigan State winning 79-67.
According to our model, Michigan State (-10.5) has a 54% chance of covering the spread, while the 146.5-point over/under has an equal 50-50 chance of hitting.
Ohio State vs. Michigan State odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Ohio State | Michigan State |
|---|---|---|
| Spread | +10.5 (-115) | -10.5 (-102) |
| Moneyline | +455 | -600 |
| Total | o146.5 (-105) | u146.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Ohio State vs. Michigan State picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Michigan State -10.5 | -102 |
| Moneyline | Michigan State | -600 |
| Total | Over 146.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Michigan State -10.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Ohio State vs. Michigan State game-day updates and essential details
Sunday's men's college basketball action between Michigan State and Ohio State at Jack Breslin Students Events Center is scheduled to commence at 1:00 PM ET.
- Who: Ohio State vs. Michigan State
- Date: Sunday, February 22, 2026
- Time: 1:00 PM ET/10:00AM PT
- Venue: Jack Breslin Students Events Center
Conclusion
We predict Michigan State, with an 86% win probability, will likely beat Ohio State on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Ohio State vs. Michigan State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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