CFB- Predictions
South Dakota vs. Mercer Prediction, Picks and Odds
Our in-depth analysis offers a comprehensive prediction for the South Dakota vs. Mercer NCAAF game on December 6, 2025. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

Game Prediction Article
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Matchup Overview
- Teams: South Dakota vs. Mercer
- Date: Saturday, December 6, 2025
- Time: 12:00 PM ET
- Venue: Five Star Stadium
Current Betting Odds
- Spread: Mercer favored at -5.5
- Total (Over/Under): 54.5
- Moneyline Odds: South Dakota +185, Mercer -220
Dimers' Win Probabilities
- South Dakota: 40%
- Mercer: 60%
Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.
Projected Final Score
Our predicted final score for this college football matchup is South Dakota 26-31 Mercer.
This prediction is based on each team's average score following 10,000 game simulations.
Our Prediction: Who Wins?
After extensive simulations, our model gives South Dakota a win probability of 40%, while Mercer has a win probability of 60%.
Summary
According to our analysis, Mercer is more likely to beat South Dakota in CFB action at Five Star Stadium on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.
Our South Dakota vs. Mercer predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.
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