LSU vs. Duke Prediction, Picks and Odds

LSU vs. Duke: Detailed Breakdown

Matchup Overview

• Teams: LSU vs. Duke
• Date: Thursday, December 4, 2025
• Time: 9:00 PM ET
• Venue: Cameron Indoor Stadium

Current Betting Odds

• Spread: LSU favored at -15.5
• Total (Over/Under): 148.5
• Moneyline Odds: LSU -2000, Duke +1200

Dimers' Win Probabilities

• LSU: 75%
• Duke: 25%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this Women's College Basketball matchup is LSU 72-66 Duke.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives LSU a win probability of 75%, while Duke has a win probability of 25%.

Summary

According to our analysis, LSU is more likely to beat Duke in CBB action at Cameron Indoor Stadium on Friday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our LSU vs. Duke predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert Women's College Basketball predictions and the best Women's College Basketball bets today for more insights and betting opportunities.

Our in-depth analysis includes Women's College Basketball futures, as well as constantly updated Women's College Basketball odds and the latest Women's College Basketball news.