Alexei Popyrin vs. Matteo Berrettini prediction, odds, picks for ATP Italian Open 2026

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Written by Ryan Leaver

Get Popyrin vs Berrettini predictions for ATP Italian Open.

Alexei Popyrin vs Matteo Berrettini Tennis Prediction.
Our Alexei Popyrin and Matteo Berrettini tennis prediction is based on thousands of simulations of the upcoming match.

Alexei Popyrin and Matteo Berrettini will lock horns in the round of 128 of the ATP Italian Open event on Thursday.

Based on updated simulations, Dimers' advanced tennis model projects Matteo Berrettini as the most likely winner of the Popyrin vs. Berrettini match.

This article offers a closer look at Thursday's match, including best bets and picks.

Popyrin vs. Berrettini prediction: Who will win and advance to the second round?

Using powerful machine learning and data analysis, we have simulated the result of Thursday's Popyrin-Berrettini men's singles match, forming part of our tennis predictions coverage.

Our famous predictive model gives Berrettini a 64% chance of beating Popyrin at the ATP Italian Open tournament.

Additionally, Berrettini has a 60% chance of winning the first set. The simulations also show Berrettini (-2.5) has a 53% chance of covering the games spread, while the under 23.5 games has a 56% chance of hitting, according to our model.

 

Alexei Popyrin vs. Matteo Berrettini odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type Popyrin Berrettini
Moneyline +198 -220
First Set +137 -175
Game Spread +2.5 (+100) -2.5 (-132)
Total Games o23.5 (-102) u23.5 (-132)

All odds are correct at the time of publication and are subject to change.

Popyrin vs. Berrettini picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Moneyline Popyrin +198
First Set Berrettini -132

According to our tennis best bets, the top play to make on this match is Alexei Popyrin to win.

Although Popyrin is less than likely to win, he provides the best value at the current available odds.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Popyrin vs. Berrettini updates and essential details

The ATP Italian Open match between Alexei Popyrin and Matteo Berrettini is scheduled to commence on Thursday at 5:00 AM ET.

  • Who: Alexei Popyrin vs. Matteo Berrettini
  • Date: Thursday, May 7, 2026
  • Approx. Time: 5:00 AM ET/2:00AM PT
  • Tournament: ATP Rome, Italy Men's Singles 2026
  • Round: Round of 128

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Conclusion

We predict Matteo Berrettini, with a 64% win probability, will likely beat Alexei Popyrin at the ATP Italian Open tournament.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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