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Read Article Diamondbacks vs. Cubs prediction: Why Cubs are favored to win Saturday's MLB matchup [5/2/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Arizona Diamondbacks vs Chicago Cubs predictions for MLB Saturday.
The Chicago Cubs will square off with the Arizona Diamondbacks in MLB action at Wrigley Field on Saturday, commencing at 2:20 PM ET.
Shota Imanaga (2-2, 2.88 ERA) will be on the bump for the Cubs, while the Diamondbacks have opted for Ryne Nelson (1-2, 7.71 ERA).
Based on updated simulations, Dimers' proven MLB model predicts the Cubs as the most likely winner of the Diamondbacks vs. Cubs game.
This article offers further insights into Saturday's matchup, including best bets and picks.
Diamondbacks vs. Cubs prediction: Who will win and cover?
Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's MLB game between the Diamondbacks and Cubs, forming part of our MLB predictions coverage.
Our independent predictive model currently gives the Cubs a 57% chance of beating the Diamondbacks.
According to our model, the Diamondbacks (+1.5) have a 61% chance of covering the run line, while the 7.5-run over/under has a 51% chance of going over.
Diamondbacks vs. Cubs odds [5/2/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Diamondbacks | Cubs |
|---|---|---|
| Run Line | +1.5 (-160) | -1.5 (+135) |
| Moneyline | +140 | -169 |
| Total | o7.5 (+110) | u7.5 (-146) |
All odds are correct at the time of publication and are subject to change.
Diamondbacks vs. Cubs picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Diamondbacks +1.5 | -160 |
| Moneyline | Diamondbacks | +140 |
| Total | Over 7.5 | +110 |
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Diamondbacks vs. Cubs game-day updates and essential details
Saturday's MLB matchup between the Cubs and Diamondbacks at Wrigley Field is scheduled to begin at 2:20 PM ET.
- Who: Arizona Diamondbacks vs. Chicago Cubs
- Date: Saturday, May 2, 2026
- Time: 2:20 PM ET/11:20AM PT
- Venue: Wrigley Field
Conclusion
We predict the Cubs, with a 57% win probability, will likely beat the Diamondbacks in Saturday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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