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Arkansas vs. LSU prediction: LSU favored to win in college football Week 12, 2025

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Written by Mac Douglass

Get Arkansas vs LSU predictions for college football Saturday.

Arkansas-LSU Predictions and Game Preview.
Arkansas vs. LSU college football gameday prediction for Saturday, November 15, 2025.

LSU will face Arkansas in Week 12 college football action at Tiger Stadium on Saturday, commencing at 12:45PM ET.

Based on the latest simulation results, Dimers' proven college football model predicts LSU as the most likely winner of the Arkansas vs. LSU game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Arkansas vs. LSU prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Arkansas vs. LSU 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives LSU a 57% chance of beating Arkansas. Our predicted final score has LSU winning 29-26.

According to our model, Arkansas (+4.5) has a 59% chance of covering the spread, while the 58.5-point over/under has a 51% chance of going over.

 

Arkansas vs. LSU odds

We have sourced the best College Football odds in America for this game, which are listed here:

Bet Type Arkansas LSU
Spread +4.5 (-110) -4.5 (-110)
Moneyline +156 -185
Total o58.5 (-105) u58.5 (-110)

All odds are correct at the time of publication and are subject to change.

Arkansas vs. LSU picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Arkansas +4.5 -110
Moneyline Arkansas +156
Total Over 58.5 -105

According to our college football best bets, the top play to make on this game is Arkansas +4.5 at the spread.

 

Arkansas vs. LSU game-day updates and essential details

Saturday's college football action between LSU and Arkansas at Tiger Stadium is scheduled to commence at 12:45PM ET.

  • Who: Arkansas vs. LSU
  • Date: Saturday, November 15, 2025
  • Time: 12:45PM ET/9:45AM PT
  • Venue: Tiger Stadium

Sports betting deal available for NCAAF Saturday

To make the most of Saturday's enormous day of sports, headlined by clashes like this one for college football Saturday, check out details on the latest Bet365 bonus code "DIMERS" that secures $200 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict LSU, with a 57% win probability, will likely beat Arkansas on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Arkansas vs. LSU insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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