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Coastal Carolina vs. South Carolina prediction: South Carolina favored to win in college football Week 13, 2025

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Written by Mac Douglass

Get Coastal Carolina vs South Carolina predictions for college football Saturday.

Coastal Carolina-South Carolina Predictions and Game Preview.
Coastal Carolina vs. South Carolina college football gameday prediction for Saturday, November 22, 2025.

South Carolina will square off with Coastal Carolina in Week 13 college football action at Williams-Brice Stadium on Saturday, commencing at 4:15PM ET.

Based on the latest simulations, Dimers' advanced college football model projects South Carolina as the most likely winner of the Coastal Carolina vs. South Carolina game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Coastal Carolina vs. South Carolina prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Coastal Carolina vs. South Carolina 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives South Carolina a 94% chance of beating Coastal Carolina. Our predicted final score has South Carolina winning 37-14.

According to our model, the bookmakers have got it right, and Coastal Carolina and South Carolina each have a 50% chance of covering the spread, while the over/under total of 50.5 points has a 56% chance of staying under.

 

Coastal Carolina vs. South Carolina odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type Coastal Carolina South Carolina
Spread +23.5 (+100) -23.5 (-118)
Moneyline +1400 -3000
Total o50.5 (-110) u50.5 (-110)

All odds are correct at the time of publication and are subject to change.

Coastal Carolina vs. South Carolina picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Coastal Carolina +23.5 +100
Moneyline Coastal Carolina +1400
Total Under 50.5 -110

According to our college football best bets, the top play to make on this game is Under 50.5 total points.

 

Coastal Carolina vs. South Carolina game-day updates and essential details

Saturday's college football matchup between South Carolina and Coastal Carolina at Williams-Brice Stadium is scheduled to start at 4:15PM ET.

  • Who: Coastal Carolina vs. South Carolina
  • Date: Saturday, November 22, 2025
  • Time: 4:15PM ET/1:15PM PT
  • Venue: Williams-Brice Stadium

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Conclusion

We predict South Carolina, with a 94% win probability, will likely beat Coastal Carolina on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Coastal Carolina vs. South Carolina insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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