College football picks today: Week 17 Friday best bets include Memphis vs. North Carolina State play [12/19/2025]

Memphis +3.5 (-108)

• Edge: 6.3%
• Probability: 58.2%
• Matchup: Memphis vs. North Carolina State (2:30PM ET, Friday)

Our model has identified value on Memphis +3.5 at -108 odds. A 58.2% probability produces an edge of 6.3%, making this the strongest play for today's college football slate.

Memphis ML (+145)

• Edge: 4.5%
• Probability: 45.4%
• Matchup: Memphis vs. North Carolina State (2:30PM ET, Friday)

Memphis ML carries a 4.5% edge and a probability of 45.4% at +145 odds, according to our model.

Alabama vs. Oklahoma over 40.5 points (-105)

• Edge: 3.6%
• Probability: 54.8%
• Matchup: Alabama vs. Oklahoma (8:00PM ET, Friday)

Alabama vs. Oklahoma over 40.5 points at -105 odds shows a 3.6% edge, supported by a 54.8% probability in simulations.

Memphis vs. North Carolina State over 56.5 points (-110)

• Edge: 3.3%
• Probability: 55.7%
• Matchup: Memphis vs. North Carolina State (2:30PM ET, Friday)

A 3.3% edge and 55.7% probability make Memphis vs. North Carolina State over 56.5 points at a value play in the Memphis vs. North Carolina State matchup, per our model.

Oklahoma ML (-112)

• Edge: 2.7%
• Probability: 55.6%
• Matchup: Alabama vs. Oklahoma (8:00PM ET, Friday)

Oklahoma ML at -112 odds presents a 2.7% edge, with simulations resulting in a probability of 55.6%.

Kennesaw State vs. Western Michigan under 47.5 points (-110)

• Edge: 2.6%
• Probability: 55%
• Matchup: Kennesaw State vs. Western Michigan (11:00AM ET, Friday)

Our model finds value on under 47.5 points in Kennesaw State vs. Western Michigan at -110 odds, supported by an edge of 2.6%.

NCAAF best bets summary: Friday, 12/19/2025

As of 7:02AM ET, here are our top college football bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Memphis vs. North Carolina State	Memphis +3.5	-108 @ DraftKings	6.3%	58.2%
Memphis vs. North Carolina State	Memphis ML	+145 @ BetMGM	4.5%	45.4%
Alabama vs. Oklahoma	Over 40.5 Points	-105 @ DraftKings	3.6%	54.8%
Memphis vs. North Carolina State	Over 56.5 Points	-110 @ BetMGM	3.3%	55.7%
Alabama vs. Oklahoma	Oklahoma ML	-112 @ FanDuel	2.7%	55.6%
Kennesaw State vs. Western Michigan	Under 47.5 Points	-110 @ FanDuel	2.6%	55%

List of upcoming college football games to bet on now

• Kennesaw State vs. Western Michigan (11:00AM ET, Friday)
• Memphis vs. North Carolina State (2:30PM ET, Friday)
• Alabama vs. Oklahoma (8:00PM ET, Friday)

More college football betting

For further insights into this week's NCAAF action, check out the latest from the Dimers Sports Betting Podcast:

Conclusion

Our college football best bets are locked and loaded for December 19, 2025, featuring plays such as Memphis +3.5 and Memphis ML. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college football insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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