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Duke vs. Virginia prediction: Virginia favored to win ACC Championship, 2025

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Written by Mac Douglass

Get Duke vs Virginia predictions for college football Saturday.

Duke-Virginia Predictions and Game Preview.
Duke vs. Virginia college football gameday prediction for Saturday, December 6, 2025.

Virginia and Duke will meet in the 2025 ACC Championship Game at Bank of America Stadium on Saturday, with kickoff at 8:00PM ET.

Based on the latest simulation results, Dimers' proven college football model predicts Virginia as the most likely winner of the Duke vs. Virginia game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

ACC Championship Game prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the result of Duke vs. Virginia 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Virginia a 60% chance of beating Duke. Our predicted final score has Virginia winning 30-26.

According to our model, the bookmakers have got it right, and Duke and Virginia each have a 50% chance of covering the spread, while the over/under total of 58.5 points has a 54% chance of going over.

 

Duke vs. Virginia odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type Duke Virginia
Spread +3.5 (-105) -3.5 (-105)
Moneyline +145 -172
Total o58.5 (-105) u58.5 (-110)

All odds are correct at the time of publication and are subject to change.

Duke vs. Virginia picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Duke +3.5 -105
Moneyline Duke +145
Total Over 58.5 -105

According to our college football best bets, the top play to make on this game is Over 58.5 total points.

 

Duke vs. Virginia game-day updates and essential details

Saturday's college football game between Virginia and Duke at Bank of America Stadium is scheduled to commence at 8:00PM ET.

  • Who: Duke vs. Virginia
  • Date: Saturday, December 6, 2025
  • Time: 8:00PM ET/5:00PM PT
  • Venue: Bank of America Stadium

 

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Conclusion

We predict Virginia, with a 60% win probability, will likely beat Duke on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Duke vs. Virginia insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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