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Florida vs. Ole Miss prediction: Why Mississippi is favored to win in college football Week 12, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Florida vs Ole Miss predictions for college football Saturday.
Mississippi will face Florida in Week 12 college football action at Vaught-Hemingway Stadium on Saturday, starting at 7:00PM ET.
Based on updated simulations, Dimers' advanced college football model predicts Mississippi as the most likely winner of the Florida vs. Ole Miss game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Florida vs. Ole Miss prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Florida vs. Ole Miss 10,000 times as part of our college football predictions coverage.
Our famous predictive model currently gives Mississippi a 69% chance of defeating Florida. Our predicted final score has Mississippi winning 29-22.
According to our model, Florida (+10.5) has a 56% chance of covering the spread, while the over/under total of 53.5 points has a 55% chance of going over.
Florida vs. Ole Miss odds
We have sourced the best College Football odds in America for this game, which are listed here:
| Bet Type | Florida | Ole Miss |
|---|---|---|
| Spread | +10.5 (-110) | -10.5 (-108) |
| Moneyline | +375 | -440 |
| Total | o53.5 (-110) | u53.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Florida vs. Ole Miss picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Florida +10.5 | -110 |
| Moneyline | Florida | +375 |
| Total | Over 53.5 | -110 |
According to our college football best bets, the top play to make on this game is Florida to win.
Florida vs. Ole Miss game-day updates and essential details
Saturday's college football matchup between Ole Miss and Florida at Vaught-Hemingway Stadium is scheduled to commence at 7:00PM ET.
- Who: Florida vs. Mississippi
- Date: Saturday, November 15, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Vaught-Hemingway Stadium
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To make the most of Saturday's exciting day of sports, headlined by clashes like this one for college football Saturday, check out details on the latest Bet365 bonus code "DIMERS" that unlocks $200 in bonus bets from a $5 bet — win or lose. Don't miss out!
Conclusion
We predict Mississippi, with a 69% win probability, will likely beat Florida on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Florida vs. Mississippi insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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