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Illinois vs. Vanderbilt prediction: Vanderbilt favored to win women's March Madness Second Round matchup [3/23/2026]

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Written by Ryan Leaver

Get Illinois vs Vanderbilt predictions for college basketball Monday.

Illinois-Vanderbilt Predictions and Game Preview.
Illinois vs. Vanderbilt March Madness prediction for Monday, March 23, 2026.

Vanderbilt will square off with Illinois in March Madness Second Round action at Memorial Gymnasium on Monday, beginning at 7:00 PM ET.

Based on the latest simulations, Dimers' new women's basketball model predicts Vanderbilt as the most likely winner of the Illinois vs. Vanderbilt game.

This article offers an expanded analysis of Monday's matchup, including best bets and picks.

Illinois vs. Vanderbilt prediction: Who will win and advance to the Sweet Sixteen?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Monday's NCAAW Tournament game between Illinois and Vanderbilt 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model currently gives Vanderbilt an 86% chance of beating Illinois.

According to our model, the over/under total of 152.5 points has a 54% chance of going over.

 

Illinois vs. Vanderbilt odds

We have researched the best women's college basketball odds in America for this game, which are listed here:

Bet Type Illinois Vanderbilt
Spread +12.5 (-110) -12.5 (-110)
Moneyline +550 -800
Total o152.5 (-110) u152.5 (-110)

All odds are correct at the time of publication and are subject to change.

Illinois vs. Vanderbilt picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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