Iowa State vs. Colorado prediction: Why Iowa State is favored to win in college football Week 7, 2025

Colorado will take on Iowa State in Week 7 college football action at Folsom Field on Saturday, beginning at 3:30PM ET.

Based on the latest simulation results, Dimers' proven college football model projects the Iowa State as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Iowa State vs. Colorado predictions page.

Iowa State vs. Colorado prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Iowa State vs. Colorado 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Iowa State a 53% chance of beating Colorado. Our predicted final score has Iowa State winning 25-24.

According to our model, Colorado (+3) has a 58% chance of covering the spread, while the 51.5-point over/under has a 56% chance of going over.

Iowa State vs. Colorado odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Iowa State	Colorado
Spread	-3 (-110)	+3 (-110)
Moneyline	-148	+130
Total	o51.5 (-115)	u51.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Iowa State vs. Colorado picks and best bets

Our model's biggest edge in today's Iowa State vs. Colorado matchup is on the over/under.

Our expert predictions, matched against the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Iowa State vs. Colorado game-day updates and essential details

Saturday's college football game between Colorado and Iowa State at Folsom Field is scheduled to commence at 3:30PM ET.

• Who: Iowa State vs. Colorado
• Date: Saturday, October 11, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Folsom Field

Dimers' comprehensive preview of Saturday's Iowa State vs. Colorado matchup includes our prediction, picks and the latest betting odds.

Before making any Iowa State vs. Colorado picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Iowa State, with a 53% win probability, will likely beat Colorado on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Iowa State vs. Colorado insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on college football

Keep up with the latest college football news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds offer the latest predictions for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.