Dodgers vs. Astros prediction: Dodgers favored to win Monday's MLB matchup [5/4/2026]

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Written by Jason Bevilacqua

Get Los Angeles Dodgers vs Houston Astros predictions for MLB Monday.

Los Angeles Dodgers-Houston Astros Predictions and Game Preview.
Los Angeles Dodgers vs. Houston Astros MLB prediction for Monday, May 4, 2026.

The Houston Astros and Los Angeles Dodgers are scheduled to meet in MLB action at Daikin Park on Monday, starting at 8:10 PM ET.

The Astros will have Steven Okert (0-0, 4.20 ERA) as their starting pitcher, up against Yoshinobu Yamamoto (2-2, 2.87 ERA) for the Dodgers.

Based on updated simulation results, Dimers' proven MLB model projects the Dodgers as the most likely winner of the Dodgers vs. Astros game.

This article offers further insights into Monday's matchup, including best bets and picks.

Dodgers vs. Astros prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Monday's MLB game between the Dodgers and Astros, forming part of our MLB predictions coverage.

Our famous predictive model gives the Dodgers a 60% chance of beating the Astros.

According to our model, the Astros (+1.5) have a 51% chance of covering the run line, while the over/under total of nine runs has a 54% chance of going over.

 

Dodgers vs. Astros odds [5/4/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Dodgers Astros
Run Line -1.5 (-122) +1.5 (+105)
Moneyline -199 +170
Total o9 (-115) u9 (-105)

All odds are correct at the time of publication and are subject to change.

Dodgers vs. Astros picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Astros +1.5 +105
Moneyline Astros +170
Total Over 9 -115

According to our best MLB bets, the top play to make on this game is Astros to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Dodgers vs. Astros game-day updates and essential details

Monday's MLB game between the Astros and Dodgers at Daikin Park is scheduled to commence at 8:10 PM ET.

Conclusion

We predict the Dodgers, with a 60% win probability, will likely beat the Astros in Monday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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