Minnesota vs. Ohio State prediction: Ohio State favored to win in college football Week 6, 2025

Ohio State and Minnesota will clash in Week 6 college football action at Ohio Stadium on Saturday, beginning at 7:30PM ET.

Based on updated simulations, Dimers' proven college football model predicts the Ohio State as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Minnesota vs. Ohio State predictions page.

Minnesota vs. Ohio State prediction: Who will win, cover the spread?

Using innovative machine learning and data analysis, we have simulated the result of Minnesota vs. Ohio State 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives Ohio State a 97% chance of beating Minnesota. Our predicted final score has Ohio State winning 33-9.

According to our model, Ohio State (-22.5) has a 53% chance of covering the spread, while the over/under total of 42.5 points has an equal 50-50 chance of hitting.

Minnesota vs. Ohio State odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Minnesota	Ohio State
Spread	+22.5 (-115)	-22.5 (-115)
Moneyline	+1400	-2800
Total	o42.5 (+100)	u42.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Minnesota vs. Ohio State picks and best bets

Our model's biggest edge in today's Minnesota vs. Ohio State matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Minnesota vs. Ohio State game-day updates and essential details

Saturday's college football action between Ohio State and Minnesota at Ohio Stadium is scheduled to begin at 7:30PM ET.

• Who: Minnesota vs. Ohio State
• Date: Saturday, October 4, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Ohio Stadium

Dimers' full preview of Saturday's Minnesota vs. Ohio State matchup includes our prediction, picks and the latest betting odds.

Before making any Minnesota vs. Ohio State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Ohio State, with a 97% win probability, will likely beat Minnesota on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Minnesota vs. Ohio State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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