MLB picks today: Memorial Day MLB best bets include Rockies vs. Diamondbacks play [5/23/2026]
Get MLB picks today and best bets for Saturday, May 23, 2026.

Today’s MLB picks for Memorial Day are here, with Rockies vs. Diamondbacks and Twins vs. Red Sox among the top plays identified by our model across Saturday’s MLB action.
Dimers’ predictive analytics engine runs 24/7, searching the latest baseball odds to unearth top betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of MLB best bets today [5/23, updated 12:08AM ET]
Below, you’ll find today’s top 10 baseball bets, ranked by edge for Saturday, May 23, 2026.
Rockies vs. Diamondbacks over 9.5 runs (+108)
- Edge: 7.9%
- Probability: 55.9%
- Matchup: Rockies vs. Diamondbacks (10:10PM ET, Saturday)
Our model has identified value on over 9.5 runs in Rockies vs. Diamondbacks at +108 odds. A 55.9% probability produces an edge of 7.9%, making this the strongest play for today's MLB slate.
Twins vs. Red Sox over 8.5 runs (+111)
- Edge: 6.0%
- Probability: 53.5%
- Matchup: Twins vs. Red Sox (4:10PM ET, Saturday)
Twins vs. Red Sox over 8.5 runs carries a 6.0% edge and a probability of 53.5% at +111 odds, according to our model.
Astros vs. Cubs over 7.5 runs (+106)
- Edge: 6.0%
- Probability: 54.5%
- Matchup: Astros vs. Cubs (2:20PM ET, Saturday)
Astros vs. Cubs over 7.5 runs at +106 odds shows a 6.0% edge, supported by a 54.5% probability in simulations.
Nationals vs. Braves over 8.5 runs (-106)
- Edge: 5.6%
- Probability: 57.1%
- Matchup: Nationals vs. Braves (4:10PM ET, Saturday)
A 5.6% edge and 57.1% probability make Nationals vs. Braves over 8.5 runs at a value play in the Nationals vs. Braves matchup, per our model.
Mariners vs. Royals over 8.5 runs (+100)
- Edge: 4.9%
- Probability: 54.9%
- Matchup: Mariners vs. Royals (4:10PM ET, Saturday)
Mariners vs. Royals over 8.5 runs at +100 odds presents a 4.9% edge, with simulations resulting in a probability of 54.9%.
Rays vs. Yankees over 7.5 runs (+122)
- Edge: 4.8%
- Probability: 49.8%
- Matchup: Rays vs. Yankees (1:35PM ET, Saturday)
Our model finds value on over 7.5 runs in Rays vs. Yankees at +122 odds, supported by an edge of 4.8%.
Mets vs. Marlins over 7.5 runs (-108)
- Edge: 4.7%
- Probability: 56.7%
- Matchup: Mets vs. Marlins (4:10PM ET, Saturday)
Our model has uncovered value on Mets vs. Marlins over 7.5 runs at -108 odds. A 56.7% probability produces a 4.7% edge, making this a strong play for today's MLB action.
Rangers vs. Angels over 7.5 runs (-117)
- Edge: 4.1%
- Probability: 58.1%
- Matchup: Rangers vs. Angels (10:05PM ET, Saturday)
A 4.1% edge on a 58.1% probability makes over 7.5 runs at -117 odds a solid value play in today's Rangers vs. Angels matchup.
Tigers vs. Orioles over 7.5 runs (-106)
- Edge: 3.6%
- Probability: 55.1%
- Matchup: Tigers vs. Orioles (4:05PM ET, Saturday)
Our model projects value on over 7.5 runs at -106 odds. A 55.1% probability produces a 3.6% edge, making the over the favorable side in Saturday’s matchup.
Athletics vs. Padres over 7.5 runs (-117)
- Edge: 3.4%
- Probability: 57.4%
- Matchup: Athletics vs. Padres (9:40PM ET, Saturday)
Rounding out our top 10 bets, Athletics vs. Padres over 7.5 runs at -117 odds shows a 57.4% probability and a 3.4% edge.
MLB best bets summary: Saturday, 5/23/2026
As of 12:08AM ET, here are our top MLB bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| Rockies vs. Diamondbacks | Over 9.5 Runs | +108 @ Kalshi | 7.9% | 55.9% |
| Twins vs. Red Sox | Over 8.5 Runs | +111 @ Polymarket | 6.0% | 53.5% |
| Astros vs. Cubs | Over 7.5 Runs | +106 @ Polymarket | 6.0% | 54.5% |
| Nationals vs. Braves | Over 8.5 Runs | -106 @ Polymarket | 5.6% | 57.1% |
| Mariners vs. Royals | Over 8.5 Runs | +100 @ Polymarket | 4.9% | 54.9% |
| Rays vs. Yankees | Over 7.5 Runs | +122 @ Polymarket | 4.8% | 49.8% |
| Mets vs. Marlins | Over 7.5 Runs | -108 @ Polymarket | 4.7% | 56.7% |
| Rangers vs. Angels | Over 7.5 Runs | -117 @ Kalshi | 4.1% | 58.1% |
| Tigers vs. Orioles | Over 7.5 Runs | -106 @ Polymarket | 3.6% | 55.1% |
| Athletics vs. Padres | Over 7.5 Runs | -117 @ Kalshi | 3.4% | 57.4% |
List of upcoming MLB games to bet on [5/23/2026]
- Rays vs. Yankees (1:35PM ET, Saturday)
- Astros vs. Cubs (2:20PM ET, Saturday)
- Pirates vs. Blue Jays (3:07PM ET, Saturday)
- Guardians vs. Phillies (4:05PM ET, Saturday)
- White Sox vs. Giants (4:05PM ET, Saturday)
- Tigers vs. Orioles (4:05PM ET, Saturday)
- Mariners vs. Royals (4:10PM ET, Saturday)
- Mets vs. Marlins (4:10PM ET, Saturday)
- Nationals vs. Braves (4:10PM ET, Saturday)
- Twins vs. Red Sox (4:10PM ET, Saturday)
- Dodgers vs. Brewers (7:15PM ET, Saturday)
- Athletics vs. Padres (9:40PM ET, Saturday)
- Rangers vs. Angels (10:05PM ET, Saturday)
- Rockies vs. D-Backs (10:10PM ET, Saturday)
Conclusion
Our MLB best bets are locked and loaded for May 23, 2026, featuring plays such as over 9.5 runs in the Rockies vs. Diamondbacks matchup and over 8.5 runs in the Twins vs. Red Sox matchup. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.



