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Mets vs. Cardinals prediction: Mets favored to win Tuesday's MLB matchup [3/31/2026]

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Written by Dave Garofolo

Get New York Mets vs St. Louis Cardinals predictions for MLB Tuesday.

New York Mets-St. Louis Cardinals Predictions and Game Preview.
New York Mets vs. St. Louis Cardinals MLB prediction for Tuesday, March 31, 2026.

The St. Louis Cardinals will take on the New York Mets in MLB action at Busch Stadium on Tuesday, beginning at 7:45 PM ET.

The Cardinals will have Andre Pallante (0-0, 0.00 ERA) as their starting pitcher, while the Mets have opted for Kodai Senga (0-0, 0.00 ERA).

Based on the latest simulations, Dimers' upgraded MLB model predicts the Mets as the most likely winner of the Mets vs. Cardinals game.

This article offers a closer look at Tuesday's matchup, including best bets and picks.

Mets vs. Cardinals prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Tuesday's MLB matchup between the Mets and Cardinals, forming part of our MLB predictions coverage.

Our famous predictive model currently gives the Mets a 57% chance of defeating the Cardinals.

According to our model, the Cardinals (+1.5) have a 57% chance of covering the run line, while the over/under total of 8.5 runs has a 53% chance of going over.

 

Mets vs. Cardinals odds [3/31/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Mets Cardinals
Run Line -1.5 (+115) +1.5 (-135)
Moneyline -146 +130
Total o8.5 (-105) u8.5 (-110)

All odds are correct at the time of publication and are subject to change.

Mets vs. Cardinals picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Cardinals +1.5 -135
Moneyline Cardinals +130
Total Over 8.5 -105

According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Mets vs. Cardinals game-day updates and essential details

Tuesday's MLB matchup between the Cardinals and Mets at Busch Stadium is scheduled to start at 7:45 PM ET.

Conclusion

We predict the Mets, with a 57% win probability, will likely beat the Cardinals on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Mets vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice, head to our responsible gambling hub.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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