North Dakota State vs. Illinois State prediction: Why North Dakota State is favored to win in college football Week 6, 2025

Illinois State will square off with the favored North Dakota State in Week 6 college football action at Hancock Stadium on Saturday, commencing at 7:00PM ET.

Based on updated simulations, Dimers' advanced college football model predicts the North Dakota State as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive North Dakota State vs. Illinois State predictions page.

North Dakota State vs. Illinois State prediction: Who will win, cover the spread?

Using powerful machine learning and data analysis, we have simulated the outcome of North Dakota State vs. Illinois State 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives North Dakota State a 92% chance of defeating Illinois State. Our predicted final score has North Dakota State winning 41-17.

According to our model, the bookmakers have got it right, and North Dakota State and Illinois State each have a 50% chance of covering the spread, while the 58.5-point over/under also has an equal 50-50 chance of hitting.

North Dakota State vs. Illinois State odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	North Dakota State	Illinois State
Spread	-24.5 (-110)	+24.5 (-110)
Moneyline	-4000	+1700
Total	o58.5 (-110)	u58.5 (-110)

All odds are correct at the time of publication and are subject to change.

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North Dakota State vs. Illinois State picks and best bets

Our model's biggest edge in today's North Dakota State vs. Illinois State matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

North Dakota State vs. Illinois State game-day updates and essential details

Saturday's college football matchup between Illinois State and North Dakota State at Hancock Stadium is scheduled to commence at 7:00PM ET.

• Who: North Dakota State vs. Illinois State
• Date: Saturday, October 4, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Hancock Stadium

Dimers' comprehensive preview of Saturday's North Dakota State vs. Illinois State matchup includes our prediction, picks and the latest betting odds.

Before making any North Dakota State vs. Illinois State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict North Dakota State, with a 92% win probability, will likely beat Illinois State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate North Dakota State vs. Illinois State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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