North Dakota vs. Northern Iowa prediction: North Dakota favored to win in college football Week 6, 2025

Northern Iowa will square off with the favored North Dakota in Week 6 college football action at UNI-Dome on Saturday, beginning at 5:00PM ET.

Based on the latest simulation results, Dimers' advanced college football model projects the North Dakota as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive North Dakota vs. Northern Iowa predictions page.

North Dakota vs. Northern Iowa prediction: Who will win, cover the spread?

Using trusted machine learning and data, we have simulated the result of North Dakota vs. Northern Iowa 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives North Dakota an 82% chance of defeating Northern Iowa. Our predicted final score has North Dakota winning 33-19.

According to our model, Northern Iowa (+15) has a 51% chance of covering the spread, while the 53.5-point over/under has a 52% chance of going over.

North Dakota vs. Northern Iowa odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	North Dakota	Northern Iowa
Spread	-15 (-113)	+15 (-113)
Moneyline	-550	+525
Total	o53.5 (-110)	u53.5 (-110)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

North Dakota vs. Northern Iowa picks and best bets

Our model's biggest edge in today's North Dakota vs. Northern Iowa matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

North Dakota vs. Northern Iowa game-day updates and essential details

Saturday's college football action between Northern Iowa and North Dakota at UNI-Dome is scheduled to start at 5:00PM ET.

• Who: North Dakota vs. Northern Iowa
• Date: Saturday, October 4, 2025
• Time: 5:00PM ET/2:00PM PT
• Venue: UNI-Dome

Dimers' in-depth preview of Saturday's North Dakota vs. Northern Iowa matchup includes our prediction, picks and the latest betting odds.

Before making any North Dakota vs. Northern Iowa picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Sports betting deal available for NCAAF Saturday

To make the most of Saturday's big day of sports, headlined by clashes like this one for college football Saturday, check out details on the latest Bet365 bonus code "DIMERS" that secures $200 in bonus bets from a $5 bet — win or lose.

Plus, find out all the details on the BetMGM x Dimers Pro offer which provides a great option for those looking to expand their sports betting horizons. Don't miss out!

Conclusion

We predict North Dakota, with an 82% win probability, will likely beat Northern Iowa on Saturday.

AI and automation have enhanced this article to quickly deliver accurate North Dakota vs. Northern Iowa insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Stay up-to-date with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds offer the most accurate probabilities for the national title game and major conferences.