Northern Illinois vs. Ohio prediction: Ohio favored to win in college football Week 8, 2025

Ohio will square off with Northern Illinois in Week 8 college football action at Frank Solich Field at Peden Stadium on Saturday, beginning at 3:30PM ET.

Based on updated simulations, Dimers' advanced college football model predicts the Ohio as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Northern Illinois vs. Ohio predictions page.

Northern Illinois vs. Ohio prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Northern Illinois vs. Ohio 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Ohio a 73% chance of defeating Northern Illinois. Our predicted final score has Ohio winning 26-18.

According to our model, Northern Illinois (+11.5) has a 59% chance of covering the spread, while the 42.5-point over/under has a 56% chance of staying under.

Northern Illinois vs. Ohio odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Northern Illinois	Ohio
Spread	+11.5 (-115)	-11.5 (-105)
Moneyline	+350	-425
Total	o42.5 (-105)	u42.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Northern Illinois vs. Ohio picks and best bets

Our model's strongest edge in today's Northern Illinois vs. Ohio matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Northern Illinois vs. Ohio game-day updates and essential details

Saturday's college football game between Ohio and Northern Illinois at Frank Solich Field at Peden Stadium is scheduled to begin at 3:30PM ET.

• Who: Northern Illinois vs. Ohio
• Date: Saturday, October 18, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Frank Solich Field at Peden Stadium

Dimers' full preview of Saturday's Northern Illinois vs. Ohio matchup includes our prediction, picks and the latest betting odds.

Before making any Northern Illinois vs. Ohio picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Ohio, with a 73% win probability, will likely beat Northern Illinois on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Northern Illinois vs. Ohio insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on college football

Keep up with the latest college football news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds provide the most up-to-date predictions for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.