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Notre Dame vs. Stanford prediction: Notre Dame favored to win in college football Week 14, 2025

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Written by Mac Douglass

Get Notre Dame vs Stanford predictions for college football Saturday.

Notre Dame-Stanford Predictions and Game Preview.
Notre Dame vs. Stanford college football gameday prediction for Saturday, November 29, 2025.

Stanford will take on the favored Notre Dame in Week 14 college football action at Stanford Stadium on Saturday, with kickoff at 10:30PM ET.

Based on the latest simulation results, Dimers' advanced college football model predicts Notre Dame as the most likely winner of the Notre Dame vs. Stanford game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Notre Dame vs. Stanford prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the result of Notre Dame vs. Stanford 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Notre Dame a 99% chance of defeating Stanford. Our predicted final score has Notre Dame winning 40-8.

According to our model, Stanford (+32.5) has a 54% chance of covering the spread, while the 49.5-point over/under has an equal 50-50 chance of hitting.

 

Notre Dame vs. Stanford odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type Notre Dame Stanford
Spread -32.5 (-108) +32.5 (-105)
Moneyline -9001 +4000
Total o49.5 (-112) u49.5 (-104)

All odds are correct at the time of publication and are subject to change.

Notre Dame vs. Stanford picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Stanford +32.5 -105
Moneyline Notre Dame -9001
Total Under 49.5 -104

According to our best college football bets, the top play to make on this game is Stanford +32.5 at the spread.

 

Notre Dame vs. Stanford game-day updates and essential details

Saturday's college football action between Stanford and Notre Dame at Stanford Stadium is scheduled to begin at 10:30PM ET.

  • Who: Notre Dame vs. Stanford
  • Date: Saturday, November 29, 2025
  • Time: 10:30PM ET/7:30PM PT
  • Venue: Stanford Stadium

 

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Conclusion

We predict Notre Dame, with a 99% win probability, will likely beat Stanford on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Notre Dame vs. Stanford insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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