Ohio State vs. Wisconsin prediction: Why Ohio State is favored to win in college football Week 8, 2025

Wisconsin and Ohio State will meet in Week 8 college football action at Camp Randall Stadium on Saturday, starting at 3:30PM ET.

Based on the latest simulation results, Dimers' advanced college football model projects the Ohio State as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Ohio State vs. Wisconsin predictions page.

Ohio State vs. Wisconsin prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Ohio State vs. Wisconsin 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Ohio State a 98% chance of defeating Wisconsin. Our predicted final score has Ohio State winning 33-8.

According to our model, Wisconsin (+25.5) has a 53% chance of covering the spread, while the over/under total of 41.5 points has a 56% chance of staying under.

Ohio State vs. Wisconsin odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Ohio State	Wisconsin
Spread	-25.5 (-105)	+25.5 (-115)
Moneyline	-2800	+1600
Total	o41.5 (-105)	u41.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Ohio State vs. Wisconsin picks and best bets

Our model's strongest edge in today's Ohio State vs. Wisconsin matchup is on the spread.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Ohio State vs. Wisconsin game-day updates and essential details

Saturday's college football action between Wisconsin and Ohio State at Camp Randall Stadium is scheduled to start at 3:30PM ET.

• Who: Ohio State vs. Wisconsin
• Date: Saturday, October 18, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Camp Randall Stadium

Dimers' full preview of Saturday's Ohio State vs. Wisconsin matchup includes our prediction, picks and the latest betting odds.

Before making any Ohio State vs. Wisconsin picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Ohio State, with a 98% win probability, will likely beat Wisconsin on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Ohio State vs. Wisconsin insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on college football

Stay informed with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds offer the latest probabilities for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.