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Orlando City vs. Charlotte FC prediction, odds, MLS picks [4/22/2026]
Updated: | First published:
Written by Nick Slade, Chief Content Officer
Get Orlando City vs Charlotte FC predictions for MLS Wednesday.
Orlando will take on Charlotte in MLS action on Wednesday, commencing at 7:30 PM ET.
Based on updated simulations, Dimers' proven MLS model predicts Charlotte as the most likely winner of the Orlando vs. Charlotte game.
This article offers a closer look at Wednesday's match, including best bets and picks.
Orlando City vs. Charlotte FC prediction: Who will win?
Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's MLS game between Orlando and Charlotte, forming part of our MLS predictions coverage.
Our independent predictive model indicates a 30.8% chance of Orlando winning, a 45.8% chance for Charlotte, and a 23.3% chance of a draw.
Additionally, the over/under total of 2.5 goals has a 61% chance of going over, according to our model.
Orlando City vs. Charlotte FC odds
We have researched the best MLS odds in America for this game, which are listed here:
Moneyline
| Orlando | Charlotte | Draw |
|---|---|---|
| +190 | +120 | +295 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -190 | +125 |
All odds are correct at the time of publication and are subject to change.
Orlando City vs. Charlotte FC picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Charlotte | +120 |
| Total Goals | Over 2.5 | -190 |
According to our best MLS bets, the top play to make on this game is Charlotte to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Orlando City vs. Charlotte FC: Correct score predictions
Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:
| Final Score | Probability |
|---|---|
| ORL 1-1 CLT | 10.5% |
| ORL 1-2 CLT | 9.2% |
| ORL 0-1 CLT | 7.6% |
These predictions are based on each team's average score according to our machine learning model, meaning the most likely correct score can differ from our predicted winner.
Orlando City vs. Charlotte FC game-day updates and essential details
Wednesday's matchup between Orlando and Charlotte is scheduled to begin at 7:30 PM ET.
- Who: Orlando City vs. Charlotte FC
- Date: Wednesday, April 22, 2026
- Time: 7:30 PM ET/4:30PM PT
World Cup 2026 watch: Alex Freeman (USA)
Orlando right-back Alex Freeman is firmly on the radar for USMNT fans as anticipation ramps up as we approach the FIFA World Cup 2026—a tournament driving interest in World Cup news and early conversation about who will win the World Cup. With the United States placed alongside Australia, Paraguay, and Türkiye in Group D next year, Freeman's MLS form will be monitored closely.
Conclusion
According to our computer model, Orlando has a 30.8% win probability on Wednesday, Charlotte has a 45.8% win probability, and there is a 23.3% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.
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