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Newcastle Knights vs. Penrith Panthers prediction: Panthers favored to win Sunday's NRL Round 8 matchup [4/26/2026]

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Written by Damien Souness

Get Newcastle Knights vs Penrith Panthers predictions for NRL Sunday.

Newcastle Knights-Penrith Panthers Predictions and Game Preview.
Newcastle Knights vs. Penrith Panthers NRL prediction for Sunday, April 26, 2026.

The Newcastle Knights and Penrith Panthers are scheduled to meet in the National Rugby League (NRL) at McDonald Jones Stadium on Sunday, starting at 12:00 AM ET.

Based on the latest simulations, Dimers' proven NRL model predicts the Panthers as the most likely winner of the Panthers vs. Knights game.

This article offers further insights into Sunday's matchup, including best bets and picks.

Knights vs. Panthers prediction: Who will win Round 8 game?

Using powerful machine learning and data, we have simulated the outcome of Sunday's NRL matchup between the Panthers and Knights, forming part of our NRL predictions coverage.

Our famous predictive model gives the Panthers an 83% chance of defeating the Knights.

According to our model, the Knights (+14.5) have a 52% chance of covering the spread, while the over/under total of 50.5 points has a 54% chance of staying under.

 

Panthers vs. Knights odds

We have researched the best NRL odds in America for this game, which are listed here:

Bet Type Panthers Knights
H2H (Moneyline) -400 +290
Line (Spread) -14.5 (-105) +14.5 (-120)
Total o50.5 (-108) u50.5 (-118)

All odds are correct at the time of publication and are subject to change.

Panthers vs. Knights picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Damien Souness
Chief Innovation Officer

Damien Souness leverages over 15 years of experience to create engaging content focused on sports, online gaming and wagering. As Chief Innovation Officer at Cipher Sports Technology Group, the parent company of Dimers, he offers strategic insights and innovative solutions to enhance the player experience.

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