Portland State vs. Cal Poly prediction: Why Cal Poly is favored to win in college football Week 10, 2025

Cal Poly and Portland State will meet in Week 10 college football action at Mustang Memorial Field on Saturday, beginning at 5:00PM ET.

Based on the latest simulations, Dimers' advanced college football model predicts the Cal Poly as the most likely winner of the Portland State vs. Cal Poly game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Portland State vs. Cal Poly prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the outcome of Portland State vs. Cal Poly 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Cal Poly an 85% chance of defeating Portland State. Our predicted final score has Cal Poly winning 35-19.

According to our model, Portland State (+17.5) has a 53% chance of covering the spread, while the over/under total of 55.5 points has a 52% chance of going over.

Portland State vs. Cal Poly odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Portland State	Cal Poly
Spread	+17.5 (-110)	-17.5 (-110)
Moneyline	+700	-950
Total	o55.5 (-110)	u55.5 (-110)

All odds are correct at the time of publication and are subject to change.

Portland State vs. Cal Poly picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Portland State +17.5	-110
Moneyline	Portland State	+700
Total	Over 55.5	-110

According to our college football best bets, the top play to make on this game is Portland State to win.

Portland State vs. Cal Poly game-day updates and essential details

Saturday's college football action between Cal Poly and Portland State at Mustang Memorial Field is scheduled to start at 5:00PM ET.

• Who: Portland State vs. Cal Poly
• Date: Saturday, November 1, 2025
• Time: 5:00PM ET/2:00PM PT
• Venue: Mustang Memorial Field

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Conclusion

We predict Cal Poly, with an 85% win probability, will likely beat Portland State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Portland State vs. Cal Poly insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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