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Reilly Opelka vs. Botic Van de Zandschulp prediction, odds, picks for ATP Swiss Indoors 2025

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Written by Damien Souness

Get Opelka vs Van de Zandschulp predictions for ATP Swiss Indoors.

Reilly Opelka vs Botic Van de Zandschulp Tennis Prediction.
Our Reilly Opelka and Botic Van de Zandschulp tennis prediction is based on thousands of simulations of the upcoming match.

Reilly Opelka and Botic Van de Zandschulp will lock horns in the round of 16 of the ATP Swiss Indoors event on Thursday.

Based on the latest simulation results, Dimers' advanced tennis model predicts Botic Van de Zandschulp as the most likely winner of the Opelka vs. Van de Zandschulp match.

This article offers an expanded analysis of Thursday's match, including best bets and picks.

Opelka vs. Van de Zandschulp prediction: Who will win and advance to the quarterfinals?

Using trusted machine learning and data analysis, we have simulated the result of Thursday's Opelka-Van de Zandschulp men's singles match 10,000 times as part of our tennis predictions coverage.

Our independent predictive model currently gives Van de Zandschulp a 53% chance of beating Opelka at the ATP Swiss Indoors tournament.

Additionally, Van de Zandschulp has a 52% chance of winning the first set. The simulations also show Van de Zandschulp (-0.5) has a 53% chance of covering the games spread, while the under 25.5 games has a 57% chance of hitting, according to our model.

 

Reilly Opelka vs. Botic Van de Zandschulp odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type Opelka Van de Zandschulp
Moneyline +100 -120
First Set +100 -125
Game Spread -0.5 (-118) +0.5 (-112)
Total Games o25.5 (-116) u25.5 (-116)

All odds are correct at the time of publication and are subject to change.

Opelka vs. Van de Zandschulp picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Moneyline Van de Zandschulp -120
First Set Van de Zandschulp -116

According to our tennis best bets, the top play to make on this match is Botic Van de Zandschulp to win the first set.

Opelka vs. Van de Zandschulp updates and essential details

The ATP Swiss Indoors match between Reilly Opelka and Botic Van de Zandschulp is scheduled to begin on Thursday at 10:55AM ET.

  • Who: Reilly Opelka vs. Botic Van de Zandschulp
  • Date: Thursday, October 23, 2025
  • Approx. Time: 10:55AM ET/7:55AM PT
  • Tournament: ATP Basel, Switzerland Men's Singles 2025
  • Round: Round of 16

All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.

Conclusion

We predict Botic Van de Zandschulp, with a 53% win probability, will likely beat Reilly Opelka at the ATP Swiss Indoors tournament.

AI and automation have enhanced this article to quickly deliver accurate Opelka vs. Van de Zandschulp insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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Written by
Damien Souness
Chief Innovation Officer

Damien Souness leverages over 15 years of experience to create engaging content focused on sports, online gaming and wagering. As Chief Innovation Officer at Cipher Sports Technology Group, the parent company of Dimers, he offers strategic insights and innovative solutions to enhance the player experience.

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