Solana Sierra vs. Karolina Pliskova prediction, odds, picks for WTA Madrid Open 2026

Solana Sierra will square off with Karolina Pliskova in the round of 16 at the WTA Madrid event on Monday.

Based on updated simulations, Dimers' proven tennis model predicts Karolina Pliskova as the most likely winner of the Sierra vs. Pliskova match.

This article offers an expanded analysis of Monday's match, including best bets and picks.

Sierra vs. Pliskova prediction: Who will win and advance to the quarterfinals?

Using trusted machine learning and data, we have simulated the outcome of Monday's Sierra-Pliskova women's singles match, forming part of our tennis predictions coverage.

Our leading predictive model gives Pliskova a 58% chance of defeating Sierra at the WTA Madrid Open tournament.

Additionally, Pliskova has a 56% chance of winning the first set. The simulations also show Sierra (+2.5) has a 53% chance of covering the games spread, while the **over/under of 21.5 games has an equal 50-50 chance of hitting, according to our model.

Solana Sierra vs. Karolina Pliskova odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

All odds are correct at the time of publication and are subject to change.

Sierra vs. Pliskova picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: