...
...
Read Article
USF vs. UAB prediction: South Florida favored to win in college football Week 13, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get USF vs UAB predictions for college football Saturday.
UAB will square off with the favored South Florida in Week 13 college football action at Protective Stadium on Saturday, starting at 3:00PM ET.
Based on the latest simulations, Dimers' advanced college football model projects South Florida as the most likely winner of the USF vs. UAB game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
USF vs. UAB prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the result of USF vs. UAB 10,000 times as part of our college football predictions coverage.
Our famous predictive model gives South Florida an 86% chance of defeating UAB. Our predicted final score has South Florida winning 44-23.
According to our model, the bookmakers have got it right, and South Florida and UAB each have a 50% chance of covering the spread, while the over/under total of 68.5 points also has an equal 50-50 chance of hitting.
USF vs. UAB odds
We have researched the best College Football odds in America for this game, which are listed here:
| Bet Type | USF | UAB |
|---|---|---|
| Spread | -21.5 (-105) | +21.5 (-104) |
| Moneyline | -1600 | +1200 |
| Total | o68.5 (-106) | u68.5 (-105) |
All odds are correct at the time of publication and are subject to change.
USF vs. UAB picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | UAB +21.5 | -104 |
| Moneyline | UAB | +1200 |
| Total | Under 68.5 | -105 |
According to our college football best bets, the top play to make on this game is UAB to win.
USF vs. UAB game-day updates and essential details
Saturday's college football matchup between UAB and USF at Protective Stadium is scheduled to begin at 3:00PM ET.
- Who: South Florida vs. UAB
- Date: Saturday, November 22, 2025
- Time: 3:00PM ET/12:00PM PT
- Venue: Protective Stadium
Sports betting deal available for Missouri sports fans
To make the most of the upcoming Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that scores you $365 in bonus bets from a $10 bet — win or lose. Don't miss out!
Conclusion
We predict South Florida, with an 86% win probability, will likely beat UAB on Saturday.
AI and automation have enhanced this article to quickly deliver accurate South Florida vs. UAB insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
Advertiser disclosure