Southeastern Louisiana vs. McNeese State prediction: Why Southeastern Louisiana is favored to win in college football Week 6, 2025

McNeese State will face the favored Southeastern Louisiana in Week 6 college football action at Navarre Stadium on Saturday, commencing at 7:00PM ET.

Based on updated simulation results, Dimers' advanced college football model predicts the Southeastern Louisiana as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Southeastern Louisiana vs. McNeese State predictions page.

Southeastern Louisiana vs. McNeese State prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the outcome of Southeastern Louisiana vs. McNeese State 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Southeastern Louisiana a 70% chance of beating McNeese State. Our predicted final score has Southeastern Louisiana winning 31-22.

According to our model, McNeese State (+9.5) has a 51% chance of covering the spread, while the 54.5-point over/under has a 52% chance of staying under.

Southeastern Louisiana vs. McNeese State odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Southeastern Louisiana	McNeese State
Spread	-9.5 (-110)	+9.5 (-110)
Moneyline	-325	+295
Total	o54.5 (+102)	u54.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Southeastern Louisiana vs. McNeese State picks and best bets

Our model's strongest edge in today's Southeastern Louisiana vs. McNeese State matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Southeastern Louisiana vs. McNeese State game-day updates and essential details

Saturday's college football game between McNeese State and Southeastern Louisiana at Navarre Stadium is scheduled to begin at 7:00PM ET.

• Who: Southeastern Louisiana vs. McNeese State
• Date: Saturday, October 4, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Navarre Stadium

Dimers' full preview of Saturday's Southeastern Louisiana vs. McNeese State matchup includes our prediction, picks and the latest betting odds.

Before making any Southeastern Louisiana vs. McNeese State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Southeastern Louisiana, with a 70% win probability, will likely beat McNeese State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Southeastern Louisiana vs. McNeese State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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