Southern Miss vs. East Carolina CBB Predictions and Odds - Dec 21, 2021

College Basketball action continues on Tuesday at 12:00PM EST as Southern Miss looks to defy the odds against East Carolina at Minges Coliseum.

Dimers' top betting picks for Southern Miss vs. East Carolina, plus game predictions and best odds, are featured in this article.

Who will win Southern Miss vs. East Carolina?

Based on state-of-the-art computer power and data, Dimers.com has simulated Tuesday's Southern Miss-East Carolina NCAA Basketball matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives East Carolina an 86% chance of getting the W against Southern Miss.

MORE: Southern Miss vs. East Carolina Simulated 10,000 Times

Point Spread, Moneyline and Over/Under

East Carolina is the -12.5 favorite versus Southern Miss, with -105 at PointsBet the best odds available.

For the underdog Southern Miss (+12.5) to cover the spread, BetMGM has the best odds on offer at -110.

PointsBet has the best moneyline odds for East Carolina at -720. That means you can risk $720 to win $100, for a total payout of $820, if it gets the W.

On the other hand, FanDuel Sportsbook has the best moneyline odds for Southern Miss at +610, where you can bet $100 to profit $610, earning a total payout of $710, if it wins.

The Over/Under for total points scored sits at 134.5 with PointsBet, which has the best odds for the Over at -105, while FanDuel Sportsbook has the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best College Basketball odds and lines.

According to DimersBOT, Southern Miss (+12.5) is a 58% chance of covering the spread, while the Over/Under total of 134.5 points is considered an equal 50-50 chance of hitting.

MORE: Live Win Probabilities for All Major College Sports

Best Bets for Southern Miss vs. East Carolina

• Spread: Southern Miss +12.5 at -110 with BetMGM (58% probability) 🔥
• Moneyline: East Carolina Win at -720 with PointsBet (86% probability)
• Over/Under: Over 134.5 at -105 with PointsBet (50% probability)

When you see a 🔥, that means it's one of our best free picks today across all major pro and college sports.

Southern Miss vs. East Carolina Score Prediction

Dimers.com's predicted final score for Southern Miss vs. East Carolina at Minges Coliseum on Tuesday has East Carolina winning 71-61.

Use our widget below to explore the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Tuesday's Southern Miss-East Carolina matchup, including pre-game predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so check this page for any changes to our betting insights ahead of Southern Miss vs. East Carolina on Tuesday December 21, 2021.

Risk-Free Bet for Southern Miss vs. East Carolina

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

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This offer is available to all new FanDuel Sportsbook users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Southern Miss vs. East Carolina 2021 CBB Game Info

When does East Carolina play Southern Miss in College Basketball?

• Date: Tuesday December 21, 2021
• Time: 12:00PM EST / 9:00AM PST
• Venue: Minges Coliseum

Want to join an online sportsbook and start betting on College Basketball? Check out the best sports betting promos in your state.

What other CBB games are on today?

Now you've got the 411 on Southern Miss vs. East Carolina, get the latest betting coverage for all upcoming NCAA Basketball games in Dimers' College Basketball Bet Hub. There you can find probabilities and odds, plus our best bets for every single CBB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!