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St Louis City vs. San Jose Earthquakes prediction, odds, MLS picks [4/25/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get St Louis City vs San Jose Earthquakes predictions for MLS Saturday.
St Louis City and San Jose will lock horns in MLS action at CITYPARK on Saturday, with kickoff at 8:30 PM ET.
Based on the latest simulation results, Dimers' proven MLS model predicts San Jose as the most likely winner of the St Louis City vs. San Jose.
This article offers a closer look at Saturday's match, including best bets and picks.
St Louis City vs. San Jose Earthquakes prediction: Who will win?
Using trusted machine learning and data, we have simulated the result of Saturday's MLS matchup between St Louis City and San Jose, forming part of our MLS predictions coverage.
Our independent predictive model currently suggests a 37.7% chance of St Louis City winning, a 38.4% chance for San Jose, and a 23.9% chance of a draw.
Additionally, the over/under total of 2.5 goals has a 60% chance of going over, according to our model.
St Louis City vs. San Jose Earthquakes odds
We have researched the best MLS odds in America for this game, which are listed here:
Moneyline
| St Louis City | San Jose | Draw |
|---|---|---|
| +145 | +160 | +290 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -185 | +130 |
All odds are correct at the time of publication and are subject to change.
St Louis City vs. San Jose Earthquakes picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | San Jose | +160 |
| Total Goals | Under 2.5 | +130 |
According to our best MLS bets, the top play to make on this game is San Jose to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
St Louis City vs. San Jose Earthquakes: Correct score predictions
The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:
| Final Score | Probability |
|---|---|
| STL 1-1 SJE | 10.8% |
| STL 1-2 SJE | 8.4% |
| STL 2-1 SJE | 8.3% |
These predictions are based on each team's average score according to our machine learning model, which means the most likely correct score can differ from our predicted winner.
St Louis City vs. San Jose Earthquakes game-day updates and essential details
Saturday's matchup between St Louis City and San Jose in MLS at CITYPARK is scheduled to commence at 8:30 PM ET.
- Who: St Louis City vs. San Jose Earthquakes
- Date: Saturday, April 25, 2026
- Time: 8:30 PM ET/5:30PM PT
- Venue: CITYPARK
Conclusion
According to our computer model, St Louis City has a 37.7% win probability on Saturday, San Jose has a 38.4% win probability, and there is a 23.9% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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