Stanford vs. SMU prediction: Southern Methodist favored to win in college football Week 7, 2025

Southern Methodist will face Stanford in Week 7 college football action at Gerald J. Ford Stadium on Saturday, starting at 12:00PM ET.

Based on updated simulations, Dimers' proven college football model predicts the Southern Methodist as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Stanford vs. SMU predictions page.

Stanford vs. SMU prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the outcome of Stanford vs. SMU 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Southern Methodist an 89% chance of defeating Stanford. Our predicted final score has Southern Methodist winning 36-16.

According to our model, the bookmakers have got it right, and Stanford and Southern Methodist each have a 50% chance of covering the spread, while the 55.5-point over/under has a 54% chance of going over.

Stanford vs. SMU odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Stanford	SMU
Spread	+19.5 (-110)	-19.5 (-105)
Moneyline	+750	-1100
Total	o55.5 (-105)	u55.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Stanford vs. SMU picks and best bets

Our model's strongest edge in today's Stanford vs. SMU matchup is on the spread.

Our expert predictions, matched against the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Stanford vs. SMU game-day updates and essential details

Saturday's college football game between SMU and Stanford at Gerald J. Ford Stadium is scheduled to start at 12:00PM ET.

• Who: Stanford vs. Southern Methodist
• Date: Saturday, October 11, 2025
• Time: 12:00PM ET/9:00AM PT
• Venue: Gerald J. Ford Stadium

Dimers' comprehensive preview of Saturday's Stanford vs. SMU matchup includes our prediction, picks and the latest betting odds.

Before making any Stanford vs. SMU picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Southern Methodist, with an 89% win probability, will likely beat Stanford on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Stanford vs. Southern Methodist insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on college football

Keep up with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds offer the most up-to-date predictions for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.