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Syracuse vs. Louisville prediction: Louisville favored to win women's basketball matchup [3/6/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Syracuse vs Louisville predictions for college basketball Friday.
Women's college basketball action continues on Friday at 5:00 PM ET as Syracuse takes on the favored Louisville at Gas South Arena.
Based on updated simulations, Dimers' new women's basketball model predicts Louisville as the most likely winner of the Syracuse vs. Louisville game.
This article offers an expanded analysis of Friday's matchup, including best bets and picks.
Syracuse vs. Louisville prediction: Who will win?
Using trusted machine learning and data, we have simulated the outcome of Friday's women's basketball matchup between Syracuse and Louisville 10,000 times as part of our women's college basketball predictions coverage.
Our leading predictive model currently gives Louisville a 79% chance of defeating Syracuse.
According to our model, the over/under total of 143.5 points has a 51% chance of staying under.
Syracuse vs. Louisville odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Syracuse | Louisville |
|---|---|---|
| Spread | +11.5 (-102) | -11.5 (-118) |
| Moneyline | +455 | -625 |
| Total | o143.5 (-110) | u143.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Syracuse vs. Louisville picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Syracuse +11.5 | -102 |
| Moneyline | Syracuse | +455 |
| Total | Under 143.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Syracuse to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Syracuse vs. Louisville game-day updates and essential details
Friday's women's basketball action between Louisville and Syracuse at Gas South Arena is scheduled to start at 5:00 PM ET.
- Who: Syracuse vs. Louisville
- Date: Friday, March 6, 2026
- Time: 5:00 PM ET/2:00PM PT
- Venue: Gas South Arena
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Conclusion
We predict Louisville, with a 79% win probability, will likely beat Syracuse on Friday.
AI and automation have enhanced this article to quickly deliver accurate Syracuse vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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