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Tennessee State vs. Charleston Southern prediction: Why Charleston Southern is favored to win in college football Week 13, 2025

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Written by Mac Douglass

Get Tennessee State vs Charleston Southern predictions for college football Saturday.

Tennessee State-Charleston Southern Predictions and Game Preview.
Tennessee State vs. Charleston Southern college football gameday prediction for Saturday, November 22, 2025.

Charleston Southern and Tennessee State will meet in Week 13 college football action at Buccaneer Field on Saturday, beginning at 2:00PM ET.

Based on the latest simulations, Dimers' advanced college football model projects Charleston Southern as the most likely winner of the Tennessee State vs. Charleston Southern game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Tennessee State vs. Charleston Southern prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Tennessee State vs. Charleston Southern 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives Charleston Southern a 73% chance of defeating Tennessee State. Our predicted final score has Charleston Southern winning 26-18.

According to our model, Tennessee State (+11.5) has a 58% chance of covering the spread, while the over/under total of 43.5 points has a 57% chance of staying under.

 

Tennessee State vs. Charleston Southern odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type Tennessee State Charleston Southern
Spread +11.5 (-110) -11.5 (-110)
Moneyline +455 -530
Total o43.5 (-110) u43.5 (-110)

All odds are correct at the time of publication and are subject to change.

Tennessee State vs. Charleston Southern picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Tennessee State +11.5 -110
Moneyline Tennessee State +455
Total Under 43.5 -110

According to our college football best bets, the top play to make on this game is Tennessee State to win.

 

Tennessee State vs. Charleston Southern game-day updates and essential details

Saturday's college football game between Charleston Southern and Tennessee State at Buccaneer Field is scheduled to start at 2:00PM ET.

  • Who: Tennessee State vs. Charleston Southern
  • Date: Saturday, November 22, 2025
  • Time: 2:00PM ET/11:00AM PT
  • Venue: Buccaneer Field

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Conclusion

We predict Charleston Southern, with a 73% win probability, will likely beat Tennessee State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Tennessee State vs. Charleston Southern insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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