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UCLA vs. Duke prediction: UCLA favored to win Thanksgiving Day women's college basketball matchup [11/27/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get UCLA vs Duke predictions for college basketball Thursday.
Women's college basketball action continues on Thanksgiving Day at 10:30PM ET as the favored UCLA takes on Duke at Michelob ULTRA Arena.
Based on updated simulations, Dimers' new women's basketball model predicts UCLA as the most likely winner of the UCLA vs. Duke game.
This article offers a closer look at Thursday's matchup, including best bets and picks.
UCLA vs. Duke prediction: Who will win?
Using trusted machine learning and data, we have simulated the result of Thursday's women's basketball matchup between UCLA and Duke 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model gives UCLA a 74% chance of beating Duke.
According to our model, the 127.5-point over/under has a 56% chance of staying under.
UCLA vs. Duke odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | UCLA | Duke |
|---|---|---|
| Spread | -12.5 (-110) | +12.5 (-110) |
| Moneyline | -952 | +680 |
| Total | o127.5 (-110) | u127.5 (-110) |
All odds are correct at the time of publication and are subject to change.
UCLA vs. Duke picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Duke +12.5 | -110 |
| Moneyline | Duke | +680 |
| Total | Under 127.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Duke to win.
UCLA vs. Duke game-day updates and essential details
Thursday's women's basketball game between Duke and UCLA at Michelob ULTRA Arena is scheduled to commence at 10:30PM ET.
- Who: UCLA vs. Duke
- Date: Thursday, November 27, 2025 (Thanksgiving Day)
- Time: 10:30PM ET/7:30PM PT
- Venue: Michelob ULTRA Arena
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Conclusion
We predict UCLA, with a 74% win probability, will likely beat Duke on Thanksgiving Day.
AI and automation have enhanced this article to quickly deliver accurate UCLA vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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