Wake Forest vs. Virginia Tech prediction: Virginia Tech favored to win in college football Week 6, 2025

Virginia Tech and Wake Forest will clash in Week 6 college football action at Lane Stadium on Saturday, starting at 1:00PM ET.

Based on the latest simulation results, Dimers' proven college football model predicts the Virginia Tech as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Wake Forest vs. Virginia Tech predictions page.

Wake Forest vs. Virginia Tech prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the outcome of Wake Forest vs. Virginia Tech 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Virginia Tech a 61% chance of defeating Wake Forest. Our predicted final score has Virginia Tech winning 27-22.

According to our model, Wake Forest (+5.5) has a 52% chance of covering the spread, while the 45.5-point over/under has a 57% chance of going over.

Wake Forest vs. Virginia Tech odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Wake Forest	Virginia Tech
Spread	+5.5 (-110)	-5.5 (-105)
Moneyline	+175	-196
Total	o45.5 (-120)	u45.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Wake Forest vs. Virginia Tech picks and best bets

Our model's strongest edge in today's Wake Forest vs. Virginia Tech matchup is on the spread.

Our expert predictions, aligned with the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Wake Forest vs. Virginia Tech game-day updates and essential details

Saturday's college football action between Virginia Tech and Wake Forest at Lane Stadium is scheduled to commence at 1:00PM ET.

• Who: Wake Forest vs. Virginia Tech
• Date: Saturday, October 4, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Lane Stadium

Dimers' full preview of Saturday's Wake Forest vs. Virginia Tech matchup includes our prediction, picks and the latest betting odds.

Before making any Wake Forest vs. Virginia Tech picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Virginia Tech, with a 61% win probability, will likely beat Wake Forest on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Wake Forest vs. Virginia Tech insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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