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Ohio State vs. Illinois Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Ohio State vs. Illinois NCAAF game on October 11, 2025. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Ohio State
Predicted score
33
:
19
Oct 11, 4PM Memorial Stadium (Champaign, IL)
Illinois
Oct 11, 4PM Memorial Stadium (Champaign, IL)
Game PredictionsPre-Game
Dimers Pro Best Bets
Pre-Game Probabilities Last Updated: 7:44PM, Oct 8
Spread
Over / Under
Moneyline
Ohio State
Illinois +14.5
Spread
50%
50%
Illinois
Ohio State OSU
Illinois +14.5
Spread
50%
50%
Illinois ILL

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Ohio State vs. Illinois: Detailed Breakdown

Matchup Overview

  • Teams: Ohio State vs. Illinois
  • Date: Saturday, October 11, 2025
  • Time: 12:00 PM ET
  • Venue: Memorial Stadium (Champaign, IL)

Current Betting Odds

  • Spread: Ohio State favored at -14.5
  • Total (Over/Under): 49.5
  • Moneyline Odds: Ohio State -650, Illinois +490

Dimers' Win Probabilities

  • Ohio State: 83%
  • Illinois: 17%

Dimers.com's predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Ohio State 33-19 Illinois.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Ohio State a win probability of 83%, while Illinois has a win probability of 17%.

Summary

According to our analysis, Ohio State is more likely to beat Illinois in CFB action at Memorial Stadium (Champaign, IL) on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Ohio State vs. Illinois predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.

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