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Michigan vs. Southern California Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Michigan vs. Southern California NCAAF game on October 11, 2025. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Michigan
Predicted score
26
:
30
Oct 11, 11:30PM Los Angeles Memorial Coliseum
Southern California
Oct 11, 11:30PM Los Angeles Memorial Coliseum
Game PredictionsPre-Game
Dimers Pro Best Bets
Pre-Game Probabilities Last Updated: 9:44AM, Oct 7
Spread
Over / Under
Moneyline
Michigan
Southern California -2.5
Spread
41%
59%
Southern California
Michigan MICH
Southern California -2.5
Spread
41%
59%
Southern California USC

Game Prediction Article

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Michigan vs. Southern California: Detailed Breakdown

Matchup Overview

  • Teams: Michigan vs. Southern California
  • Date: Saturday, October 11, 2025
  • Time: 7:30 PM ET
  • Venue: Los Angeles Memorial Coliseum

Current Betting Odds

  • Spread: Southern California favored at -2.5
  • Total (Over/Under): 57.5
  • Moneyline Odds: Michigan +115, Southern California -134

Dimers' Win Probabilities

  • Michigan: 40%
  • Southern California: 60%

Dimers.com's predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Michigan 26-30 Southern California.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Michigan a win probability of 40%, while Southern California has a win probability of 60%.

Summary

According to our analysis, Southern California is more likely to beat Michigan in CFB action at Los Angeles Memorial Coliseum on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Michigan vs. Southern California predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.

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