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Cardinals vs. Texans prediction: Houston favored to win in NFL Week 15 [2025]

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Written by Dave Garofolo

Get Arizona Cardinals vs Houston Texans predictions for NFL Sunday.

Arizona Cardinals-Houston Texans Predictions and Game Preview.
Arizona Cardinals vs. Houston Texans NFL prediction for Sunday, December 14, 2025.

NFL Week 15 action continues on Sunday at 1:00PM ET as the Arizona Cardinals square off with the Houston Texans at NRG Stadium.

Based on updated simulation results, Dimers' proven NFL model projects the Texans as the most likely winner of the Cardinals vs. Texans game.

This article offers an expanded analysis of Sunday's matchup, including projected touchdown scorers, best bets and player prop picks.

Cardinals vs. Texans prediction: Who will win and cover?

Since our Cardinals-Texans predictions earlier in the week, we have simulated the outcome of Sunday's NFL game between the Cardinals and Texans 10,000 times as part of our NFL predictions coverage.

Our leading predictive model currently gives the Texans an 82% chance of defeating the Cardinals in Week 15 of the NFL season. Our predicted final score has the Texans winning 25-16.

According to our model, the Cardinals (+10.5) have a 54% chance of covering the spread, while the 42.5-point over/under has an equal 50-50 chance of hitting.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 15 straight up picks.

Cardinals vs. Texans odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type Cardinals Texans
Spread +10.5 (-110) -10.5 (-102)
Moneyline +455 -550
Total o42.5 (-108) u42.5 (-110)

All odds are correct at the time of publication and are subject to change.

Cardinals vs. Texans picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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