Arizona Cardinals vs. Los Angeles Rams updated prediction featuring Trey McBride, Kyren Williams [Week 18, 2026]

Dimers' latest NFL predictions are live for Los Angeles Rams vs. Arizona Cardinals in Week 18, with our model giving the Rams a 76% of winning.

As Sunday approaches, both teams have updated their injury reports. A few lineup decisions are still up in the air, and those could shape how each side approaches this NFC West matchup.

Since our early Rams-Cardinals predictions, we’ve updated the win probabilities, score projections, and TD odds for Trey McBride, Kyren Williams, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—head to our Cardinals vs. Rams page.

What's changed? Arizona vs. LA Rams updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Cardinals vs. Rams matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Cardinals 24%, Rams 76%
• Predicted Final Score: Cardinals 19-26 Rams
• Spread: Cardinals (+7.5) 50%, Rams (-7.5) 50%
• Total Points (46.5): Over 51%, Under 49%

As of January 1, 2026, these Cardinals-Rams figures reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 18 highlight the top candidates to find the end zone in Cardinals-Rams on Sunday:

Arizona Cardinals

• Trey McBride: 39.8% probability
• Michael Wilson: 34.7% probability
• Emari Demercado: 22.5% probability

Los Angeles Rams

• Kyren Williams: 49.4% probability
• Puka Nacua: 42.1% probability
• Blake Corum: 36.1% probability

Cardinals vs. Rams latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Cardinals +7.5 (-115), Rams -7.5 (-102)
• Moneyline: Cardinals +280, Rams -325
• Total: Over/Under 46.5 (-105/-110)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Cardinals vs. Rams Week 18 details

The NFL Week 18 action between the Rams and Cardinals at SoFi Stadium is scheduled for January 4, 2026.

• Who: Arizona Cardinals vs. Los Angeles Rams
• Date: Sunday, January 4, 2026
• Time: 4:25 PM ET/1:25PM PT
• Venue: SoFi Stadium

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Conclusion

We predict the Rams, with a 76% win probability, will likely beat the Cardinals in Week 18 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Cardinals vs. Rams matchup, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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