CBB Parlay Picks for Sweet Sixteen March Madness games on Thursday, March 26

The Sweet Sixteen round of the 2026 CBB Tournament begins today, Thursday, March 26 with the first batch of games, and Dimers has teamed up with bet365 Sportsbook to bring you data-backed boosted CBB bets during each round of the tournament, from today's CBB parlay all the way through the National Championship in Indianapolis on April 6.

Dimers runs thousands of simulations for every CBB matchup, providing users with win probabilities, spread projections, college basketball player props, and total predictions for each game, so you're never flying blind, especially with the new Dimers App where you can unlock a free three-day trial of Dimers Pro today, giving you every single value bet across each day of the tournament.

For an example, see how we use the Dimers CBB player projections to find these four CBB player props to bet on today.

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How to find Dimers CBB bets in the Dimers App

Each day of the tournament, Dimers will identify the best betting value in each CBB tournament game, with our college basketball predictions covering the following markets:

• Moneyline predictions for every tournament game
• Against the spread (ATS) picks backed by simulation data
• Point total (over/under) projections
• Player props (points, rebounds, assists, and more)

Dimers Pros have complete access to daily predictions on the Dimers website and in the Dimers App, so don't miss out on your three-day free trial to give you insights across the tournament's opening rounds.

CBB Parlay Picks Today - Thursday, March 26

We've selected these picks using a combination of Dimers CBB best bets and game predictions to find a combination of value and probability that gives us the best chance to win our CBB parlay.

Today's parlay targets a pair of favorites that our model gives at least a 75% probability to win and a 55% probability cover their respective spread, boosting their odds with bet365.

CBB Parlay Bet: Purdue to win by 6 or more

Game: Vanderbilt vs. Nebraska

Time: 7:10 PM ET

With a projected final score of 79-71 and a 55% probability to cover -7.5, Purdue looks poised to win this matchup by at least six points.

Purdue has been on an absolute tear from three-point range, and that's precisely the matchup problem Texas can't solve.

If they stay hot from deep and maintain an advantage on the glass, the Longhorns simply won't be able to generate enough offense to keep pace.

Texas's best-case scenario is a defensive effort that's hard to replicate on short rest against a team this hot, and our model projects Purdue stars Fletcher Loyer and Trey Kaufman-Renn to push 20 points each in a dominant outing.

CBB Parlay Bet: Arizona to win by 6 or more

Game: Arizona vs. Arkansas

Time: 9:45 PM ET

Arkansas may have made a little Cinderella run to the Sweet 16, but now they run into a buzzsaw. At a 54.8% probability for Arizona to cover -8.5, in a projected final score of 85-76, the Wildcats are well in play for a six-point win.

Arizona may be the best team in the country, even if we rank them as third-best 1-seed remaining.

The Razorbacks love to get to the paint, but Arizona's interior defense ranks second nationally in opponent two-point field goal percentage, holding teams to just 43.7%.

On the flipside, Arizona gets an Arkansas defense that ranks 278th in opponent two-point percentage allowed.

Add in Brayden Burries potentially going off against the 200th-ranked defense in the country - he is our second-highest projected scorer tonight - and Arizona just may cruise to the Elite Eight.

Boosted CBB Parlay Odds

Thanks to bet365 sportsbook, we get boosted odds on this CBB parlay, to raise it from odds of +155 to +200 for an even bigger payout.

Grab this boost at bet365 and good luck if tailing along today and for the rest of the tournament!

Our boosted parlay at bet365 - odds subject to change.

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