Reds vs. Pirates prediction: Why Pittsburgh is favored to win Sunday's MLB matchup [6/28/2026]

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Written by Dave Garofolo

Get Cincinnati Reds vs Pittsburgh Pirates predictions for MLB Sunday.

Cincinnati Reds-Pittsburgh Pirates Predictions and Game Preview.
Cincinnati Reds vs. Pittsburgh Pirates MLB prediction for Sunday, June 28, 2026.

The Pittsburgh Pirates will square off with the Cincinnati Reds, in what is expected to be a tight MLB game, at PNC Park on Sunday, commencing at 1:35 PM ET.

Mitch Keller (5-5, 4.89 ERA) will start for the Pirates, pitting him against Brady Singer (3-6, 4.81 ERA) for the Reds.

Based on the latest simulation results, Dimers' advanced MLB model gives the Pirates a slight edge with a 54.7% win probability over the Reds.

This article offers an expanded analysis of Sunday's Reds vs. Pirates matchup, including best bets and picks.

Reds vs. Pirates prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Sunday's MLB game between the Reds and Pirates, forming part of our MLB predictions coverage.

Our famous predictive model currently gives the Pirates a 54.7% chance of beating the Reds.

According to our model, the Reds (+1.5) have a 62.3% chance of covering the run line, while the 8.5-run over/under has a 55.2% chance of going over,.

 

Reds vs. Pirates odds [6/28/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Reds Pirates
Run Line +1.5 (-187) -1.5 (+158)
Moneyline +113 -132
Total o8.5 (-120) u8.5 (+102)

All odds are correct at the time of publication and are subject to change.

Reds vs. Pirates picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Pirates -1.5 +158
Moneyline Reds +113
Total Over 8.5 -120

According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Reds vs. Pirates game-day updates and essential details

Sunday's MLB action between the Pirates and Reds at PNC Park is scheduled to begin at 1:35 PM ET.

Conclusion

We predict the Pirates, with a 54.7% win probability, will likely beat the Reds in Sunday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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