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Nuggets vs. Pacers prediction: Why Denver is favored to win Wednesday's NBA matchup [12/3/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Denver Nuggets vs Indiana Pacers predictions for NBA Wednesday.
The Indiana Pacers and Denver Nuggets will lock horns in NBA action at Gainbridge Fieldhouse on Wednesday, with tipoff at 7:00PM ET.
Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the Nuggets as the most likely winner of the Nuggets vs. Pacers game.
This prediction follows the latest NBA Injury Report, which suggests the Pacers lineup will feature players like Pascal Siakam, Bennedict Mathurin and Andrew Nembhard, while the Nuggets will look to Nikola Jokic, Jamal Murray and Cameron Johnson.
This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Nuggets vs. Pacers prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's NBA matchup between the Nuggets and Pacers 10,000 times as part of our NBA predictions coverage.
Our leading predictive model currently gives the Nuggets a 72% chance of beating the Pacers. Our predicted final score has the Nuggets winning 122-115.
According to our model, the Pacers (+8.5) have a 55% chance of covering the spread, while the 238.5-point over/under has a 53% chance of staying under.
Nuggets vs. Pacers odds
We have researched the best NBA odds in America for this game, which are listed here:
| Bet Type | Nuggets | Pacers |
|---|---|---|
| Spread | -8.5 (-105) | +8.5 (-115) |
| Moneyline | -300 | +260 |
| Total | o238.5 (-105) | u238.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Nuggets vs. Pacers picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pacers +8.5 | -115 |
| Moneyline | Pacers | +260 |
| Total | Under 238.5 | -115 |
According to our best NBA bets for Wednesday, the top play to make on this game is Pacers +8.5 at the spread.
Nuggets vs. Pacers player props
Betting on Nuggets vs. Pacers NBA player props? We have crunched the numbers to project how each team's leading players will perform at Gainbridge Fieldhouse.
Nikola Jokic is expected to lead the Nuggets with 27 points, 13 rebounds and 10 assists, while Pascal Siakam is projected to have 22 points, 6 rebounds and 4 assists for the Pacers.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Nuggets prediction
Our model's projected player stats for the Nuggets are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Nikola Jokic | 27 | 13 | 10 | 2 | 64 |
| Jamal Murray | 23 | 4 | 6 | 2 | 43 |
| Cameron Johnson | 18 | 5 | 3 | 2 | 33 |
| Peyton Watson | 12 | 6 | 2 | 1 | 30 |
| Tim Hardaway | 12 | 3 | 2 | 2 | 21 |
Pacers prediction
Projected points, rebounds, assists and three-pointers made for the Pacers:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Pascal Siakam | 22 | 6 | 4 | 1 | 41 |
| B. Mathurin | 20 | 6 | 2 | 2 | 35 |
| Andrew Nembhard | 15 | 3 | 6 | 2 | 33 |
| Jay Huff | 12 | 5 | 2 | 2 | 27 |
| T.J. McConnell | 11 | 3 | 5 | 0 | 26 |
Nuggets vs. Pacers game-day updates and essential details
Wednesday's matchup between the Pacers and Nuggets at Gainbridge Fieldhouse is scheduled to begin at 7:00PM ET.
- Who: Denver Nuggets vs. Indiana Pacers
- Date: Wednesday, December 3, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Gainbridge Fieldhouse
Conclusion
We predict the Nuggets, with a 72% win probability, will likely beat the Pacers on Wednesday, with Nikola Jokic projected for a game-high 64 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Nuggets vs. Pacers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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