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Pistons vs. Celtics prediction: Detroit favored to win Wednesday's NBA Cup game [11/26/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Detroit Pistons vs Boston Celtics predictions for NBA Wednesday.
The Boston Celtics and Detroit Pistons will meet in NBA Cup action at TD Garden on Wednesday, starting at 5:00PM ET.
Based on the latest simulations and today’s injury reports, Dimers' proven NBA model projects the Pistons as the most likely winner of the Pistons vs. Celtics game.
This prediction follows the latest NBA Injury Report, which suggests the Celtics lineup will feature stars like Jaylen Brown, Payton Pritchard and Derrick White, while the Pistons will rely on Cade Cunningham, Jalen Duren and Ausar Thompson.
This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Pistons vs. Celtics prediction: Who will win NBA Cup game?
Using trusted machine learning and data analysis, we have simulated the result of Wednesday's NBA matchup between the Pistons and Celtics 10,000 times as part of our NBA predictions coverage.
Our famous predictive model currently gives the Pistons a 62% chance of beating the Celtics. Our predicted final score has the Pistons winning 116-113.
According to our model, the Pistons (-2.5) have a 52% chance of covering the spread, while the 230.5-point over/under has a 51% chance of staying under.
Pistons vs. Celtics odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Pistons | Celtics |
|---|---|---|
| Spread | -2.5 (-108) | +2.5 (-106) |
| Moneyline | -148 | +130 |
| Total | o230.5 (-114) | u230.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Pistons vs. Celtics picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pistons -2.5 | -108 |
| Moneyline | Pistons | -148 |
| Total | Under 230.5 | -105 |
According to our NBA best bets, the top play to make on this game is Pistons to win.
Pistons vs. Celtics player props
Betting on Detroit vs. Boston NBA prop bets? We use the best information available to project how each team's leading players will perform at TD Garden.
Cade Cunningham is expected to lead the Pistons with 25 points, 6 rebounds and 8 assists, while Jaylen Brown is projected to have 25 points, 6 rebounds and 4 assists for the Celtics.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Pistons prediction
Our model's projected player stats for the Pistons are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Cade Cunningham | 25 | 6 | 8 | 2 | 50 |
| Jalen Duren | 17 | 12 | 2 | 0 | 39 |
| Ausar Thompson | 13 | 5 | 3 | 0 | 29 |
| Duncan Robinson | 12 | 3 | 2 | 3 | 22 |
| Tobias Harris | 11 | 4 | 2 | 1 | 23 |
Celtics prediction
Projected points, rebounds, assists and three-pointers made for the Celtics:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Jaylen Brown | 25 | 6 | 4 | 2 | 44 |
| P. Pritchard | 17 | 4 | 4 | 3 | 32 |
| Derrick White | 16 | 4 | 5 | 3 | 36 |
| Anfernee Simons | 14 | 2 | 3 | 2 | 25 |
| Chris Boucher | 11 | 5 | 1 | 2 | 23 |
Pistons vs. Celtics game-day updates and essential details
Wednesday's game between the Celtics and Pistons at TD Garden is scheduled to commence at 5:00PM ET.
- Who: Detroit Pistons vs. Boston Celtics
- Date: Wednesday, November 26, 2025
- Time: 5:00PM ET/2:00PM PT
- Venue: TD Garden
- Tournament details: 2025 Emirates NBA Cup
Conclusion
We predict the Pistons, with a 62% win probability, will likely beat the Celtics on Wednesday, with Cade Cunningham projected for a game-high 50 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Pistons vs. Celtics insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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