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Pistons vs. Pacers prediction: Why Detroit is favored to win Monday's NBA matchup [11/24/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Detroit Pistons vs Indiana Pacers predictions for NBA Monday.
The Indiana Pacers will take on the favored Detroit Pistons in NBA action at Gainbridge Fieldhouse on Monday, beginning at 7:00PM ET.
Based on updated simulations and today’s injury reports, Dimers' proven NBA model predicts the Pistons as the most likely winner of the Pistons vs. Pacers game.
This prediction follows the latest NBA Injury Report, which suggests the Pacers lineup will feature players like Pascal Siakam, Bennedict Mathurin and Andrew Nembhard, while the Pistons will look to Cade Cunningham, Jalen Duren and Ausar Thompson.
This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Pistons vs. Pacers prediction: Who will win and cover?
As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Monday's clash between the Pistons and Pacers.
Our famous predictive model currently gives the Pistons a 77% chance of defeating the Pacers. Our predicted final score has the Pistons winning 121-113.
According to our model, the Pacers (+9.5) have a 55% chance of covering the spread, while the 236.5-point over/under has a 52% chance of staying under.
Pistons vs. Pacers odds
We have researched the best NBA odds in America for this game, which are listed here:
| Bet Type | Pistons | Pacers |
|---|---|---|
| Spread | -9.5 (-110) | +9.5 (-105) |
| Moneyline | -400 | +333 |
| Total | o236.5 (-110) | u236.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Pistons vs. Pacers picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pacers +9.5 | -105 |
| Moneyline | Pacers | +333 |
| Total | Under 236.5 | -105 |
According to our best NBA bets for Monday, the top play to make on this game is Pacers +9.5 at the spread.
Pistons vs. Pacers player props
NBA prop bets are a common way to wager on the Pistons vs. Pacers game without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Gainbridge Fieldhouse.
Cade Cunningham is expected to lead the Pistons with 28 points, 5 rebounds and 9 assists, while Pascal Siakam is projected to have 23 points, 6 rebounds and 5 assists for the Pacers.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Pistons prediction
Our model's projected player stats for the Pistons are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Cade Cunningham | 28 | 5 | 9 | 2 | 54 |
| Jalen Duren | 17 | 12 | 3 | 0 | 40 |
| Ausar Thompson | 13 | 5 | 2 | 0 | 28 |
| Duncan Robinson | 12 | 2 | 2 | 3 | 21 |
| Tobias Harris | 12 | 5 | 2 | 1 | 24 |
Pacers prediction
Projected points, rebounds, assists and three-pointers made for the Pacers:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Pascal Siakam | 23 | 6 | 5 | 2 | 44 |
| B. Mathurin | 21 | 6 | 2 | 2 | 37 |
| Andrew Nembhard | 16 | 3 | 5 | 2 | 32 |
| T.J. McConnell | 9 | 3 | 3 | 0 | 20 |
| Isaiah Jackson | 9 | 6 | 1 | 0 | 23 |
Pistons vs. Pacers game-day updates and essential details
Monday's action between the Pacers and Pistons at Gainbridge Fieldhouse is scheduled to commence at 7:00PM ET.
- Who: Detroit Pistons vs. Indiana Pacers
- Date: Monday, November 24, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Gainbridge Fieldhouse
Conclusion
We predict the Pistons, with a 77% win probability, will likely beat the Pacers on Monday, with Cade Cunningham projected for a game-high 54 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Pistons vs. Pacers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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