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Drexel vs. Charleston prediction: Why Charleston is favored to win men's college basketball matchup [12/29/2025]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Drexel vs Charleston predictions for college basketball Monday.
Charleston will square off with Drexel in men's college basketball action at TD Arena on Monday, commencing at 7:00 PM ET.
Based on updated simulations, Dimers' advanced college basketball model projects Charleston as the most likely winner of the Drexel vs. Charleston game.
This article offers a closer look at Monday's matchup, including an expanded look at the predicted score, best bets and picks.
Drexel vs. Charleston prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the result of Monday's NCAA basketball matchup between Drexel and Charleston 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives Charleston a 79% chance of defeating Drexel. Our predicted final score has Charleston winning 76-68.
According to our model, Drexel (+9.5) has a 55% chance of covering the spread, while the 142.5-point over/under has a 54% chance of going over.
Drexel vs. Charleston odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Drexel | Charleston |
|---|---|---|
| Spread | +9.5 (-118) | -9.5 (-102) |
| Moneyline | +360 | -440 |
| Total | o142.5 (-105) | u142.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Drexel vs. Charleston picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Drexel +9.5 | -118 |
| Moneyline | Drexel | +360 |
| Total | Over 142.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Over 142.5 total points.
Drexel vs. Charleston game-day updates and essential details
Monday's men's college basketball action between Charleston and Drexel at TD Arena is scheduled to start at 7:00 PM ET.
- Who: Drexel vs. Charleston
- Date: Monday, December 29, 2025
- Time: 7:00 PM ET/4:00PM PT
- Venue: TD Arena
Conclusion
We predict Charleston, with a 79% win probability, will likely beat Drexel on Monday.
AI and automation have enhanced this article to quickly deliver accurate Drexel vs. Charleston insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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