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Illinois State vs. Southern Illinois prediction: Southern Illinois favored to win men's college basketball matchup [12/18/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Illinois State vs Southern Illinois predictions for college basketball Thursday.
Southern Illinois will square off with Illinois State in men's college basketball action at Banterra Center on Thursday, commencing at 9:00 PM ET.
Based on the latest simulations, Dimers' advanced college basketball model predicts Southern Illinois as the most likely winner of the Illinois State vs. Southern Illinois game.
This article offers a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and picks.
Illinois State vs. Southern Illinois prediction: Who will win and cover?
Using trusted machine learning and statistical analysis, we have simulated the result of Thursday's NCAA basketball matchup between Illinois State and Southern Illinois 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Southern Illinois a 55% chance of beating Illinois State. Our predicted final score has Southern Illinois winning 77-75.
According to our model, the bookies have got it right, and Illinois State and Southern Illinois each have a 50% chance of covering the spread, while the 153.5-point over/under has a 53% chance of staying under.
Illinois State vs. Southern Illinois odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Illinois State | Southern Illinois |
|---|---|---|
| Spread | +1.5 (-110) | -1.5 (+100) |
| Moneyline | +105 | -110 |
| Total | o153.5 (-112) | u153.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Illinois State vs. Southern Illinois picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Southern Illinois -1.5 | +100 |
| Moneyline | Southern Illinois | -110 |
| Total | Under 153.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Southern Illinois to win.
Illinois State vs. Southern Illinois game-day updates and essential details
Thursday's men's college basketball game between Southern Illinois and Illinois State at Banterra Center is scheduled to begin at 9:00 PM ET.
- Who: Illinois State vs. Southern Illinois
- Date: Thursday, December 18, 2025
- Time: 9:00 PM ET/6:00PM PT
- Venue: Banterra Center
Conclusion
We predict Southern Illinois, with a 55% win probability, will likely beat Illinois State on Thursday.
AI and automation have enhanced this article to quickly deliver accurate Illinois State vs. Southern Illinois insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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