Iowa vs. Iowa State prediction: Why Iowa State is favored to win men's college basketball matchup [12/11/2025]

Men's college basketball action continues on Thursday at 8:00PM ET as Iowa squares off with Iowa State in men's college basketball action at James H. Hilton Coliseum.

Based on the latest simulation results, Dimers' advanced college basketball model projects Iowa State as the most likely winner of the Iowa vs. Iowa State game.

This article offers further insights into Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

Iowa vs. Iowa State prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Thursday's NCAA basketball game between Iowa and Iowa State 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Iowa State an 88% chance of beating Iowa. Our predicted final score has Iowa State winning 77-64.

According to our model, Iowa State (-11.5) has a 54% chance of covering the spread, while the 141.5-point over/under has a 53% chance of going over.

Iowa vs. Iowa State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Iowa vs. Iowa State picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: