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Jacksonville Jaguars vs. Denver Broncos updated prediction featuring Travis Etienne, RJ Harvey [Week 16, 2025]
Get new expert Jaguars vs Broncos predictions for Sunday's game.

Dimers' latest NFL predictions are live for Denver Broncos vs. Jacksonville Jaguars in Week 16, with our model giving the Broncos a 59% of winning.
As Sunday approaches, both teams have updated their injury reports. Some lineup calls are still undecided, and those could shape how each side approaches this AFC matchup.
Since our early Broncos-Jaguars predictions, we’ve updated the win probabilities, score projections, and TD odds for Travis Etienne, RJ Harvey, and others.
For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our Jaguars vs. Broncos page.
What's changed? Jacksonville vs. Denver updated predictions
Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Jaguars vs. Broncos matchup stacks up. Here are the updated forecasts:
- Straight Up Win Probabilities: Jaguars 41%, Broncos 59%
- Predicted Final Score: Jaguars 21-24 Broncos
- Spread: Jaguars (+3) 56%, Broncos (-3) 44%
- Total Points (47.5): Over 48%, Under 52%
As of December 18, 2025, these Jaguars-Broncos numbers reflect changes since our early-week simulation.
Anytime touchdown scorer predictions
New NFL player projections for Week 16 highlight the top candidates to find the end zone in Jaguars-Broncos on Sunday:
Jacksonville Jaguars
- Travis Etienne: 48.9% probability
- Jakobi Meyers: 29.3% probability
- Brian Thomas: 27.9% probability
Denver Broncos
- RJ Harvey: 52.4% probability
- Courtland Sutton: 33.5% probability
- Pat Bryant: 26.3% probability
Jaguars vs. Broncos latest odds
The best current odds from the top sportsbooks in the US:
- Spread: Jaguars +3 (-105), Broncos -3 (-105)
- Moneyline: Jaguars +144, Broncos -160
- Total: Over/Under 47.5 (-102/-118)
Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.
Jaguars vs. Broncos Week 16 details
The NFL Week 16 action between the Broncos and Jaguars at Empower Field at Mile High is scheduled for December 21, 2025.
- Who: Jacksonville Jaguars vs. Denver Broncos
- Date: Sunday, December 21, 2025
- Time: 4:05 PM ET/1:05PM PT
- Venue: Empower Field at Mile High
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Conclusion
We predict the Broncos, with a 59% win probability, will likely beat the Jaguars in Week 16 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.
Enhanced by AI and automation, this article delivers quick, accurate insights on the Jaguars vs. Broncos matchup, with human oversight maintaining high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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