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La Salle vs. Pennsylvania prediction: Why Pennsylvania is favored to win men's college basketball matchup [11/29/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get La Salle vs Pennsylvania predictions for college basketball Saturday.
Men's college basketball action continues on Saturday at 4:30PM ET as La Salle takes on Pennsylvania in men's college basketball action at The Palestra.
Based on updated simulations, Dimers' proven college basketball model gives Pennsylvania a slight edge with a 54% win probability over La Salle.
This article offers further insights into Saturday's La Salle vs. Pennsylvania matchup, including an expanded look at the predicted score, best bets and picks.
La Salle vs. Pennsylvania prediction: Who will win and cover?
Using trusted machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball game between La Salle and Pennsylvania 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Pennsylvania a 54% chance of defeating La Salle. Our predicted final score has Pennsylvania winning 76-75.
According to our model, La Salle (+2.5) has a 58% chance of covering the spread, while the 149.5-point over/under has a 52% chance of going over.
La Salle vs. Pennsylvania odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | La Salle | Pennsylvania |
|---|---|---|
| Spread | +2.5 (-102) | -2.5 (-112) |
| Moneyline | +138 | -160 |
| Total | o149.5 (-110) | u149.5 (-105) |
All odds are correct at the time of publication and are subject to change.
La Salle vs. Pennsylvania picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | La Salle +2.5 | -102 |
| Moneyline | La Salle | +138 |
| Total | Over 149.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is La Salle +2.5 at the spread.
La Salle vs. Pennsylvania game-day updates and essential details
Saturday's men's college basketball action between Pennsylvania and La Salle at The Palestra is scheduled to start at 4:30PM ET.
- Who: La Salle vs. Pennsylvania
- Date: Saturday, November 29, 2025
- Time: 4:30PM ET/1:30PM PT
- Venue: The Palestra
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Conclusion
We predict Pennsylvania, with a 54% win probability, will likely beat La Salle on Saturday.
AI and automation have enhanced this article to quickly deliver accurate La Salle vs. Pennsylvania insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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